Long-Term Outcome of Photobiomodulation for Diabetic Macular Edema: A Case Report.

Macular edema is the major cause of decreased vision in patients with diabetes. Antioxidative and anti-inflammatory effects of photobiomodulation (PBM) have been reported with near-infrared irradiation. In this study, the efficacy and safety of PBM with near-infrared radiation in a patient with diabetic macular edema were assessed. We present the case of a 60-year-old man with diabetic macular edema responding to 670 nm light PBM alone. After PBM, his vision improved and macular edema resolved on optical coherence tomography (OCT) findings without adverse events. In 16 months follow-up, visual acuity remained stable and OCT showed no evidence of recurrence of edema. Six hundred seventy nanometers light PBM can be potentially considered as a therapeutic method in diabetic patients with macular edema. Also, it provides a noninvasive and nonexpensive treatment in home.