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腹腔镜肝切除术治疗化脓性肝脓肿:一项回顾性病例对照研究。

Laparoscopic hepatectomy for the treatment of pyogenic liver abscess: A retrospective case-control study.

机构信息

Department of Hepatobiliary Surgery of Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.

出版信息

Medicine (Baltimore). 2022 Nov 11;101(45):e31745. doi: 10.1097/MD.0000000000031745.

Abstract

Percutaneous catheter drainage is the first-line treatment for pyogenic liver abscess (PLA). Some patients need hepatectomy because of underling hepatobiliary pathology or unresponsiveness to nonoperative treatment, the traditional method is open hepatectomy (OH). Laparoscopic hepatectomy (LH) for PLA is rarely reported. The purpose of this study is to describe our experience of LH for treating PLA and to compare LH with OH. The medical records of patients who underwent LH for treating PLA were retrospectively analyzed, and the results were compared with those of patients with OH. From January 2015 to December 2021, 61 patients with PLA underwent hepatectomy, and 28 patients who underwent LH (LH group) were compared with 33 patients who underwent OH (OH group). There were no significant differences in the basic data between the 2 groups. Two patients in the LH group were converted to open surgery due to hemorrhage and dense perihepatic adhesions, there was no significant difference between the 2 groups in the operation time (186.2 ± 85.6 vs. 175.9 ± 76.7 minutes, P = .239), Institut Mutualiste Montsouris classification, extent of hepatectomy and drainage tube removal time, however, the blood loss (200.0 ± 100.5 vs. 470.9 ± 120.1 mL, P = .003), numerical rating scale (5.2 ± 1.8 vs. 9.1 ± 1.6, P = .042), the time to resume oral diet (12.3 ± 6.5 vs. 24.6 ± 10.2 hours, P = .005), the ambulant time (20.2 ± 7.3 vs. 40.2 ± 10.8 hours, P = .010), incidence of postoperative complications (14.3% vs.33.3%, P = .002), comprehensive complication index (46.2 vs. 60.6, P = .013), postoperative hospital stay (8.5 ± 7.3 vs. 13.5 ± 10.2 days, P = .025) in the LH group was significantly less than that in the OH group. Wit experience laparoscopic surgeons, treating PLA by LH is safe and feasible and compares favorably with OH.

摘要

经皮经肝穿刺引流是治疗细菌性肝脓肿(PLA)的一线治疗方法。由于潜在的肝胆病理或对非手术治疗无反应,一些患者需要行肝切除术,传统方法是开腹肝切除术(OH)。腹腔镜肝切除术(LH)治疗 PLA 很少有报道。本研究旨在描述我们应用 LH 治疗 PLA 的经验,并将 LH 与 OH 进行比较。回顾性分析了 61 例接受 LH 治疗 PLA 的患者的病历资料,并将结果与接受 OH 的患者进行比较。2015 年 1 月至 2021 年 12 月,61 例 PLA 患者行肝切除术,其中 28 例行 LH(LH 组),与 33 例行 OH(OH 组)比较。两组患者的基本资料无显著差异。LH 组有 2 例因出血和肝周致密粘连转为开腹手术,两组手术时间(186.2±85.6 vs. 175.9±76.7 分钟,P=0.239)、Mutualiste Montsouris 分级、肝切除范围和引流管拔除时间无显著差异,但出血量(200.0±100.5 vs. 470.9±120.1 mL,P=0.003)、数字评分法(5.2±1.8 vs. 9.1±1.6,P=0.042)、恢复口服饮食时间(12.3±6.5 vs. 24.6±10.2 小时,P=0.005)、下床活动时间(20.2±7.3 vs. 40.2±10.8 小时,P=0.010)、术后并发症发生率(14.3% vs. 33.3%,P=0.002)、综合并发症指数(46.2 vs. 60.6,P=0.013)、术后住院时间(8.5±7.3 vs. 13.5±10.2 天,P=0.025)均显著低于 OH 组。对于经验丰富的腹腔镜外科医生来说,LH 治疗 PLA 是安全可行的,与 OH 相比具有优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce3/9666222/385b6903e17c/medi-101-e31745-g001.jpg

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