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[一例新生儿重症2019冠状病毒病病例报告]

[A case report of neonatal severe coronavirus disease 2019].

作者信息

Mo Yan, Mo Jian, Liang Ru-Ying, Xiao Gao-Yuan, Li Yan, Wei Qiu-Fen

机构信息

Neonatal Medical Center, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning 530002, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2022 Nov 15;24(11):1266-1268. doi: 10.7499/j.issn.1008-8830.2208135.

DOI:10.7499/j.issn.1008-8830.2208135
PMID:36398554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9678062/
Abstract

A 7-day-old male neonate was admitted due to testing positive for SARS-CoV-2. The neonate was born through cesarian section at 40 weeks and 2 days of gestation. His mother was diagnosed with coronavirus disease 2019 (COVID-19) caused by Omicron variant infection 1 day before delivery. The neonate was separated from his mother after birth and was taken care of by his father. Three days after the neonate was born, his father was also diagnosed with COVID-19. The neonate was diagnosed with COVID-19 on day 7 of life. The neonate presented with hyperpyrexia, dyspnea, hypoxia, and feeding difficulties, and the chest CT showed the coexistence of consolidation and ground glass-like changes mainly located below the posterior pleura. He was given symptomatic support treatment such as low flow oxygen therapy and posture management after admission. He was cured and discharged after 10 days of hospitalization. This is the first reported case of neonatal severe COVID-19 caused by Omicron variant infection in China. It is necessary to take appropriate protective measures for the neonate to prevent infection when the mother or caregiver of the neonate is a suspected or confirmed cases of COVID-19.

摘要

一名7日龄男婴因新型冠状病毒检测呈阳性入院。该男婴在孕40周零2天时通过剖宫产出生。其母亲在分娩前1天被诊断为感染奥密克戎变异株所致的新型冠状病毒肺炎(COVID-19)。男婴出生后即与母亲分离,由其父亲照料。男婴出生3天后,其父亲也被诊断为COVID-19。男婴在出生第7天被诊断为COVID-19。该男婴表现为高热、呼吸困难、缺氧及喂养困难,胸部CT显示实变与磨玻璃样改变并存,主要位于后胸膜下。入院后给予低流量吸氧及体位管理等对症支持治疗。住院10天后治愈出院。这是中国首例报道的由奥密克戎变异株感染引起的新生儿重症COVID-19病例。当新生儿的母亲或照料者为COVID-19疑似或确诊病例时,有必要对新生儿采取适当的防护措施以预防感染。

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本文引用的文献

1
Management experience of a designated hospital for children with coronavirus disease 2019.2019 冠状病毒病患儿定点医院的管理经验。
Zhongguo Dang Dai Er Ke Za Zhi. 2022 Aug 15;24(8):839-845. doi: 10.7499/j.issn.1008-8830.2206068.
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[Severe pneumonia caused by coinfection of SARS-CoV-2 Omicron variant and in a child].[一名儿童感染严重急性呼吸综合征冠状病毒2奥密克戎变种合并感染导致的重症肺炎]
Zhonghua Er Ke Za Zhi. 2022 Jun 2;60(6):600-602. doi: 10.3760/cma.j.cn112140-20220430-00400.
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Coronavirus infection in neonates: a systematic review.新生儿冠状病毒感染:系统评价。
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[Application of pulmonary ultrasound in the diagnosis of COVID-19 pneumonia in neonates].[肺部超声在新生儿新型冠状病毒肺炎诊断中的应用]
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Front Immunol. 2020 Apr 24;11:879. doi: 10.3389/fimmu.2020.00879. eCollection 2020.
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[Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children].[2019冠状病毒病在婴幼儿中的临床特征及胸部CT表现]
Zhongguo Dang Dai Er Ke Za Zhi. 2020 Mar;22(3):215-220. doi: 10.7499/j.issn.1008-8830.2020.03.007.