Office of Surgical Research Administration, Department of Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX. Electronic address: https://twitter.com/MonicaFahrenho1.
Laboratory for Regenerative Tissue Repair, Division of Pediatric Surgery, Department of Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX. Electronic address: https://twitter.com/LilySCheng.
Surgery. 2023 Feb;173(2):479-484. doi: 10.1016/j.surg.2022.09.038. Epub 2022 Nov 16.
Preparing a grant proposal is no small feat, especially for research (R-series) grants from the National Institutes of Health. The National Institutes of Health is the largest public funder of biomedical research in the world, and as such, procuring a research grant from the National Institutes of Health is one of the ultimate benchmarks of success for a surgeon-scientist. Most investigators are familiar with the page limits for most R-series grants (12 pages for an R01 and 6 pages for an R21), with the addition of a single page allotted for the specific aims. Interestingly, despite the usual focus on the aforementioned research section, the rest of the application can routinely consist of an additional 100 to 150 pages, which means that pages allotted for the specific aims and research strategy represent only 10% of the complete application package. For busy surgeons, it is this abundance of ancillary documentation that can make preparing a research grant particularly onerous. Fortunately, for some, support exists within the department to help prepare much of this documentation by drawing from previous sources, templates, and boilerplate language that has been developed. Although these resources can significantly reduce the burden on individual investigators, there is a danger of leaning on generalized templates that can dilute the message of the overall grant proposal and introduce extraneous or incorrect information that can ultimately impact the cohesiveness and ultimately the competitiveness of the grant. The focus of this article is to educate surgeon-scientists regarding the purpose and importance of the ancillary information required for National Institutes of Health research grants and how to make the most of institutional resources while tailoring these materials to create a cohesive, competitive grant application.
准备一份资助提案并非易事,尤其是针对美国国立卫生研究院(NIH)的研究(R 系列)资助。NIH 是世界上最大的生物医学研究公共资助者,因此,从 NIH 获得研究资助是外科医生科学家取得成功的最终基准之一。大多数研究人员都熟悉大多数 R 系列资助的页面限制(R01 为 12 页,R21 为 6 页),另外还有一页专门用于特定目标。有趣的是,尽管通常关注上述研究部分,但申请的其余部分通常还包括另外 100 到 150 页,这意味着专门针对特定目标和研究策略的页面仅占完整申请包的 10%。对于忙碌的外科医生来说,正是这种大量的辅助文件使得准备研究资助变得特别繁重。幸运的是,对于一些人来说,部门内有支持来帮助准备这些文件,这些文件可以从以前的来源、模板和已开发的通用模板中提取。尽管这些资源可以大大减轻个别研究人员的负担,但存在依赖通用模板的危险,这些模板可能会淡化整个资助提案的信息,并引入不必要或不正确的信息,最终会影响资助的凝聚力,并最终影响资助的竞争力。本文的重点是让外科医生科学家了解 NIH 研究资助所需的辅助信息的目的和重要性,以及如何充分利用机构资源,同时根据这些材料进行调整,以创建一个有凝聚力、有竞争力的资助申请。