School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, 610054, P. R. China.
Adv Sci (Weinh). 2023 Jan;10(2):e2203870. doi: 10.1002/advs.202203870. Epub 2022 Nov 20.
Near-infrared organic photodetectors (NIR-OPDs) are significant technologies in emerging biomedicine applications for uniquely wearable, noninvasive, low-cost advantages. However, biosignals are weak and changing rapidly so practical biodetection and bioimaging are still challenging for NIR-OPDs. Herein, high-performance NIR-OPDs with synchronous optical output are realized by recombining anode-injected electrons with photogenerated holes on emitters. Owing to high detection performance of 4.5 × 10 Jones detectivity and 120 kHz -3 dB bandwidth, five arteries are monitored by transmission-type method and cardiac cycle is analyzed. Importantly, the synchronous optical output is direct emission demonstrating outstanding photon conversion efficiency approaching 20% and luminance signal-to-noise ratio over 8000. Consequently, pathology imaging is directly developed without complex readout circuits and arrays from which squamous metaplasia of cervix and carcinoma of large intestine are observed clearly. The NIR-OPD demonstrates strategies for high-performance synchronous electrical/optical output and directly imaging. Biomedicine applications implemented here are high level, representing important steps for NIR-OPDs toward providing clues for clinical diagnosis.
近红外有机光电探测器 (NIR-OPD) 在新兴的生物医学应用中具有重要意义，因为它具有独特的可穿戴、非侵入性和低成本优势。然而，生物信号很微弱且变化迅速，因此对于 NIR-OPD 来说，实际的生物检测和生物成像仍然具有挑战性。在此，通过在发射器上重新组合阳极注入的电子和光生空穴，实现了具有同步光学输出的高性能 NIR-OPD。由于具有 4.5×10 琼斯探测率和 120 kHz-3 dB 带宽的高检测性能，通过透射式方法监测了五条动脉，并分析了心动周期。重要的是，同步光学输出是直接发射，表现出接近 20%的出色光子转换效率和超过 8000 的亮度信号噪声比。因此，无需复杂的读出电路和阵列，即可直接进行病理学成像，从中可以清楚地观察到宫颈鳞状上皮化生和大肠癌。该 NIR-OPD 展示了用于高性能同步电/光输出和直接成像的策略。此处实现的生物医学应用具有较高的水平，代表着 NIR-OPD 朝着为临床诊断提供线索迈出了重要的一步。
