Raja Junaid, Madoff David C
Division of Interventional Radiology, University of Alabama at Birmingham, Birmingham, Alabama.
Division of Interventional Radiology, Yale New Haven Hospital, New Haven, Connecticut.
Semin Intervent Radiol. 2022 Nov 17;39(4):411-415. doi: 10.1055/s-0042-1758076. eCollection 2022 Aug.
The broad scope of malignancies treated in interventional oncology is mirrored by the breadth of oncotherapeutics, drugs used to treat cancer. Many of these treatments are administered endovascularly, though a group of therapies can be delivered percutaneously. Perhaps the best taxonomy of oncotherapeutics is based on their biological inactivity or activity and the mechanism by which they interact with treated and targeted tissues. As the fields of interventional oncology and oncotherapeutics continue to grow and expand, this framework may provide a more organized approach in helping distinguish and select the best therapy for patients.
介入肿瘤学所治疗的恶性肿瘤范围广泛,这与用于治疗癌症的肿瘤治疗药物种类繁多是相对应的。这些治疗方法很多是通过血管内给药,不过也有一组治疗方法可以经皮给药。也许肿瘤治疗药物的最佳分类方法是基于它们的生物无活性或活性以及它们与治疗和靶向组织相互作用的机制。随着介入肿瘤学和肿瘤治疗学领域不断发展和扩大,这个框架可能会提供一种更有条理的方法,以帮助区分和为患者选择最佳治疗方法。