肾细胞癌所致玛丽·约瑟夫修女结节：一例报告
Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report.
作者信息
Hirata Kimiko, Narabayashi Masaru, Murashima Takaya, Segawa Takehiko, Ohtsu Shuji
机构信息
Radiation Oncology, Kyoto City Hospital, Kyoto, JPN.
Urology, Kyoto City Hospital, Kyoto, JPN.
出版信息
Cureus. 2022 Oct 16;14(10):e30344. doi: 10.7759/cureus.30344. eCollection 2022 Oct.
Sister Mary Joseph's nodules (SMJNs) are umbilical skin metastases of various abdominopelvic malignancies, and they rarely originate from renal cell carcinomas. Radiotherapy is typically used to treat the nodules as a palliative intention. We report a rare case of SMJN that originated from clear cell renal cell carcinoma, which was treated with external beam radiation therapy (EBRT) and interstitial brachytherapy (ISBT). A 74-year-old male patient with a history of left renal cell carcinoma developed an umbilical nodule which was diagnosed as SMJN. The patient underwent EBRT (30 Gy in 10 fractions) and ISBT (12 Gy in two fractions), leading the nodule to complete resolution. This case report might support that radiotherapy, including ISBT, is effective for the treatment of SMJN from renal cell carcinoma.
玛丽·约瑟夫修女结节（SMJNs）是各种腹盆腔恶性肿瘤的脐部皮肤转移灶，很少起源于肾细胞癌。放射治疗通常用于姑息性治疗这些结节。我们报告一例罕见的起源于透明细胞肾细胞癌的SMJN病例，该病例采用了外照射放疗（EBRT）和组织间近距离放疗（ISBT）进行治疗。一名有左肾细胞癌病史的74岁男性患者出现一个脐部结节，被诊断为SMJN。该患者接受了EBRT（10次分割，共30 Gy）和ISBT（2次分割，共12 Gy），结节完全消退。本病例报告可能支持包括ISBT在内的放射治疗对肾细胞癌所致SMJN的治疗有效。
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