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在乌干达西南部的一家地区艾滋病毒诊所中,对 15-24 岁青少年抗逆转录病毒治疗依从性的感知障碍和促进因素:一项定性研究。

Perceived barriers and facilitators to antiretroviral therapy adherence among youth aged 15-24 years at a regional HIV clinic in SouthWestern Uganda: a qualitative study.

机构信息

Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

Department of Nursing, Mbarara University of Science and Technology, Mbarara, Uganda.

出版信息

Afr Health Sci. 2022 Jun;22(2):54-62. doi: 10.4314/ahs.v22i2.7.

DOI:10.4314/ahs.v22i2.7
PMID:36407355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9652626/
Abstract

INTRODUCTION

South-Western region has the second highest HIV prevalence in Uganda. Youth aged 15-24 have shown poor adherence to antiretroviral therapy compared to the older cohorts. Previous studies from other regions have shown various barriers and facilitators. Our study was designed to describe specific barriers and facilitators to treatment adherence among youths in a large regional HIV clinic in southwestern Uganda.

METHODS

We used a phenomenological qualitative study design conducted amongst 30 purposively selected HIV positive youth aged 15-24 years enrolled at Mbarara Regional Referral Hospital HIV clinic on ART for a period of at least one year and 6 key informants using in-depth interviews. The data was collected in an inductive manner during the period between 21st July and 17th August 2020. The recordings were backed up, transcribed verbatim and then analyzed manually using thematic content analysis.

RESULTS

The barriers to ART adherence were described in three descending categories as perceived treatment burden, perceived resultant stigma and discrimination, whereas the main facilitators were; perceived usefulness of HIV medications, availability of free services and Social support.

CONCLUSION

Youths aged 15-24 have challenges with ART associated treatment burden and fear to disclose their HIV status because of the resultant stigma from their communities. Many have however accepted the fact that HIV medications are lifesaving and are strongly motivated to adhere to their medications despite the circumstances.

摘要

简介

乌干达西南部地区的艾滋病毒感染率居全国第二。与年长的队列相比,15-24 岁的年轻人在抗逆转录病毒治疗方面的依从性较差。来自其他地区的先前研究表明存在各种障碍和促进因素。我们的研究旨在描述乌干达西南部一个大型地区 HIV 诊所中年轻人在接受治疗方面的具体障碍和促进因素。

方法

我们采用了现象学定性研究设计,在 Mbarara 地区转诊医院 HIV 诊所中,对 30 名 15-24 岁的 HIV 阳性青年进行了研究,他们接受抗逆转录病毒治疗(ART)至少一年,另外还对 6 名关键知情人进行了深入访谈。数据是在 2020 年 7 月 21 日至 8 月 17 日期间以归纳的方式收集的。录音被备份,逐字转录,然后使用主题内容分析手动进行分析。

结果

抗逆转录病毒治疗依从性的障碍被描述为三个递减的类别,即感知的治疗负担、感知的结果耻辱和歧视,而主要的促进因素是:感知 HIV 药物的有用性、免费服务的提供和社会支持。

结论

15-24 岁的年轻人在接受抗逆转录病毒治疗方面存在治疗负担的挑战,并且由于社区的耻辱感而害怕透露自己的 HIV 状况。然而,许多人已经接受了这样一个事实,即 HIV 药物是救命的,并且尽管存在各种情况,他们仍然强烈地愿意坚持服用药物。

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