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感染艾滋病毒的青少年和年轻人坚持抗逆转录病毒治疗的社会决定因素:一项范围综述

Social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV: a scoping review.

作者信息

Piran Camila Moraes Garollo, Mori Mariana Martire, Cargnin Alana Vitória Escritori, Fonseca Beatriz Sousa da, Shibukawa Bianca Machado Cruz, Merino Maria de Fátima Garcia Lopes, Frade João Manuel Graça, Furtado Marcela Demitto

机构信息

Universidade Estadual de Maringá, Programa de Pós-Graduação em Enfermagem, Maringá, PR, Brazil.

Politécnico de Leiria, Escola Superior de Saúde, Leiria, Portugal.

出版信息

Rev Esc Enferm USP. 2025 Aug 18;59:e20250026. doi: 10.1590/1980-220X-REEUSP-2025-0026en. eCollection 2025.

Abstract

OBJECTIVE

To map scientific evidence related to social determinants of adherence to antiretroviral therapy among adolescents and young people living with HIV.

METHOD

Scoping review according to JBI methodology, carried out on 20 databases. The inclusion criteria were: adolescents and young people living with HIV (10 and 24 years old), studies related to adherence to antiretroviral therapy (self-reported adherence, viral suppression, pill counts, or pharmacy refill records).

RESULTS

Thirty-nine studies were identified, published between 1999 and 2024, which allowed mapping the determinants that promote and limit adherence to treatment among adolescents and young people living with HIV, being focused on individual characteristics, lifestyle, social and community networks, living and working conditions, socioeconomic, cultural and environmental conditions (Dimensions 1 to 5).

CONCLUSION

The social determinants of adherence interact in a complex way, which affects the context of antiretroviral therapy, both positively and negatively, and are directly interconnected with the living conditions of adolescents and young people living with HIV.

摘要

目的

梳理与感染艾滋病毒的青少年和年轻人抗逆转录病毒治疗依从性的社会决定因素相关的科学证据。

方法

根据JBI方法进行范围综述,在20个数据库上开展。纳入标准为:感染艾滋病毒的青少年和年轻人(10至24岁)、与抗逆转录病毒治疗依从性相关的研究(自我报告的依从性、病毒抑制、药丸计数或药房配药记录)。

结果

共识别出39项研究,发表于1999年至2024年之间,这些研究有助于梳理促进和限制感染艾滋病毒的青少年和年轻人治疗依从性的决定因素,重点关注个体特征、生活方式、社会和社区网络、生活和工作条件、社会经济、文化和环境条件(维度1至5)。

结论

依从性的社会决定因素以复杂的方式相互作用,对抗逆转录病毒治疗的背景产生正面和负面的影响,并且与感染艾滋病毒的青少年和年轻人的生活条件直接相互关联。

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