相似文献
1
The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents.
ACS Pharmacol Transl Sci. 2022 Oct 12;5(11):1097-1108. doi: 10.1021/acsptsci.2c00097. eCollection 2022 Nov 11.
2
Studies on the affinity of 6-[(-(cyclo)aminoalkyl)oxy]-4-chromen-4-ones for sigma 1/2 receptors.
RSC Med Chem. 2021 May 20;12(6):1000-1004. doi: 10.1039/d1md00105a. eCollection 2021 Jun 23.
3
Biphenylalkoxyamine Derivatives-Histamine H Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.
Molecules. 2021 Jun 11;26(12):3580. doi: 10.3390/molecules26123580.
4
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.
Eur J Med Chem. 2019 Jul 15;174:226-235. doi: 10.1016/j.ejmech.2019.04.056. Epub 2019 Apr 21.
5
Cyanobiphenyls: Novel H receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Bioorg Chem. 2021 Sep;114:105129. doi: 10.1016/j.bioorg.2021.105129. Epub 2021 Jun 28.
6
Synthesis and pharmacological evaluation of donepezil-based agents as new cholinesterase/monoamine oxidase inhibitors for the potential application against Alzheimer's disease.
J Enzyme Inhib Med Chem. 2016;31(sup3):41-53. doi: 10.1080/14756366.2016.1201814. Epub 2016 Jul 7.
7
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities.
J Enzyme Inhib Med Chem. 2022 Dec;37(1):2605-2620. doi: 10.1080/14756366.2022.2122054.
8
Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease.
ACS Chem Neurosci. 2022 Dec 7;13(23):3488-3501. doi: 10.1021/acschemneuro.2c00520. Epub 2022 Nov 16.
9
Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease.
Bioorg Med Chem. 2022 Aug 15;68:116807. doi: 10.1016/j.bmc.2022.116807. Epub 2022 May 9.
10
Search for new multi-target compounds against Alzheimer's disease among histamine H receptor ligands.
Eur J Med Chem. 2020 Jan 1;185:111785. doi: 10.1016/j.ejmech.2019.111785. Epub 2019 Oct 17.
引用本文的文献
1
Contilisant-Belinostat Hybrids: Polyfunctionalized Indole Derivatives as Multineurotarget Drugs for the Potential Treatment of Alzheimer's Disease.
ACS Pharmacol Transl Sci. 2025 Feb 7;8(3):831-840. doi: 10.1021/acsptsci.4c00709. eCollection 2025 Mar 14.
2
One-Pot Regio- and Diastereoselective Gold-Catalyzed Propargylation of in Situ Activated Chromones and Consecutive Cyclization.
Org Lett. 2024 Dec 13;26(49):10487-10492. doi: 10.1021/acs.orglett.4c03812. Epub 2024 Nov 28.
3
Sphingoid Bases Regulate the Sigma-1 Receptor-Sphingosine and ,'-Dimethylsphingosine Are Endogenous Agonists.
Int J Mol Sci. 2023 Feb 4;24(4):3103. doi: 10.3390/ijms24043103.
本文引用的文献
1
Novel Therapeutic Target for Prevention of Neurodegenerative Diseases: Modulation of Neuroinflammation with Sig-1R Ligands.
Biomolecules. 2022 Feb 25;12(3):363. doi: 10.3390/biom12030363.
2
Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures.
ACS Med Chem Lett. 2022 Feb 18;13(3):499-506. doi: 10.1021/acsmedchemlett.2c00001. eCollection 2022 Mar 10.
3
Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer's Disease.
Front Aging Neurosci. 2022 Feb 9;14:837649. doi: 10.3389/fnagi.2022.837649. eCollection 2022.
4
Synthesis of Aminoethyl-Substituted Piperidine Derivatives as σ Receptor Ligands with Antiproliferative Properties.
ChemMedChem. 2022 Apr 5;17(7):e202100735. doi: 10.1002/cmdc.202100735. Epub 2022 Feb 9.
5
Safinamide protects against amyloid β (Aβ)-induced oxidative stress and cellular senescence in M17 neuronal cells.
Bioengineered. 2022 Jan;13(1):1921-1930. doi: 10.1080/21655979.2021.2022262.
6
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.
ACS Chem Neurosci. 2022 Jan 5;13(1):1-15. doi: 10.1021/acschemneuro.1c00435. Epub 2021 Dec 15.
7
Emerging Benefits: Pathophysiological Functions and Target Drugs of the Sigma-1 Receptor in Neurodegenerative Diseases.
Mol Neurobiol. 2021 Nov;58(11):5649-5666. doi: 10.1007/s12035-021-02524-5. Epub 2021 Aug 12.
8
Studies on the affinity of 6-[(-(cyclo)aminoalkyl)oxy]-4-chromen-4-ones for sigma 1/2 receptors.
RSC Med Chem. 2021 May 20;12(6):1000-1004. doi: 10.1039/d1md00105a. eCollection 2021 Jun 23.
9
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective.
J Med Chem. 2021 Jun 24;64(12):7926-7962. doi: 10.1021/acs.jmedchem.0c02265. Epub 2021 Jun 2.
10
Alzheimer disease.
Nat Rev Dis Primers. 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y.
Zotero 插件