以背痛为首发特征的晚期胃癌酷似多发性骨髓瘤：一例报告及文献复习
Back pain as an initial feature of advanced gastric cancer mimicking multiple myeloma: A case report and literature review.
作者信息
Ata Fateen, Yousaf Zohaib, Al Kalaji Bilal N, Ashour Anas A, Fael Mohamad, Eun Kim Gi, Bint I Bilal Ammara, Elaiwy Orwa, Jones Akhnuwkh
机构信息
Department of Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
Department of Radiology, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
出版信息
Qatar Med J. 2022 Nov 9;2022(4):53. doi: 10.5339/qmj.2022.53. eCollection 2022.
BACKGROUND
Back pain is a rare initial presentation of gastric cancer. Isolated back pain with red flags in middle-aged patients might indicate multiple myeloma. However, it is rarely present in advanced gastric adenocarcinoma; hence, data are limited to case reports only. For a timely diagnosis of the underlying malignancy, endoscopy should be considered if the initial workup for this backache is unrevealing.
CASE PRESENTATION
We present a 34-year-old previously healthy gentleman with severe unremitting backache. He was ultimately diagnosed with gastric adenocarcinoma stage IV and received palliative treatment. The manuscript also reviewed relevant literature.
CONCLUSION
In rare cases, gastric malignancy can initially present as back pain with lytic bone lesions, mimicking multiple myeloma. Endoscopy early in the course of investigations may help reduce associated morbidities. Further, more extensive studies are required to understand better the clinical characteristics, demographics, and management of such patients.
背景
背痛是胃癌罕见的首发症状。中年患者出现伴有警示信号的孤立性背痛可能提示多发性骨髓瘤。然而，在晚期胃腺癌中这种情况很少见；因此，相关数据仅局限于病例报告。为了及时诊断潜在的恶性肿瘤，如果对这种背痛的初步检查没有结果，应考虑进行内镜检查。
病例报告
我们报告一名34岁既往健康的男性，患有严重的持续性背痛。他最终被诊断为IV期胃腺癌并接受了姑息治疗。本文还回顾了相关文献。
结论
在罕见情况下，胃恶性肿瘤最初可能表现为伴有溶骨性骨病变的背痛，酷似多发性骨髓瘤。在检查过程早期进行内镜检查可能有助于降低相关发病率。此外，需要更广泛的研究以更好地了解此类患者的临床特征、人口统计学和治疗方法。
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