Division of Hospital Medicine, University of Colorado Denver, Aurora, Colorado, USA.
Adult and Child Center for Outcomes Research and Delivery Science, Aurora, Colorado, USA.
J Palliat Med. 2023 Apr;26(4):527-538. doi: 10.1089/jpm.2022.0413. Epub 2022 Nov 21.
Hospitalized patients with cancer and their caregivers discharged to skilled nursing facilities (SNFs) have unmet palliative care needs. To determine feasibility and acceptability of Assessing and Listening to Individual Goals and Needs (ALIGN), a palliative care social worker (PCSW) intervention, for older adults and their caregivers in SNFs. Single-arm, single-site pilot study. Predefined feasibility goals were >70% intervention completion and study retention rates (postintervention outcomes completed at one week). Twenty-three patients with cancer and their 21 caregivers discharged to 12 SNFs posthospitalization. Primary outcomes were feasibility and acceptability. Exploratory patient and caregiver-reported outcomes, including goals of care were collected at baseline and one week postintervention. Health care utilization, mortality, and hospice utilization was collected at the six-month follow-up. Of 73 patients screened, 35 (48%) were eligible and 23 (66%) patients and 21 caregivers enrolled. Eighteen (78%) patients completed the intervention and 10 (44%) patients and 13 (62%) caregivers provided follow-up outcomes. Average age of patients was 73, and 19 (83%) had stage III or IV cancer. Average age of caregivers was 55. Eight (44%) patients' preferences changed to prefer less aggressive care. Nineteen (83%) patients died during or shortly after intervention completion. Qualitative feedback from participant and SNF staff interviews supported high acceptability. PCSW involvement increased illness understanding and patient engagement with advance care planning. SNF staff valued increased palliative support. Intervention completion was >70%, however, not study retention due to higher-than-expected mortality. Future study should account for high mortality and examine whether ALIGN can better prepare surrogate decision makers and enhance the ability of SNFs to address changing goals of care. Clinical Trial Registration Number NCT04882111.
癌症住院患者及其照护者出院至康复护理机构(SNF)后,仍存在未满足的姑息治疗需求。本研究旨在评估姑息治疗社会工作者(PCSW)干预措施 Assessing and Listening to Individual Goals and Needs(ALIGN)在 SNF 中老年患者及其照护者中的可行性和可接受性。这是一项单臂、单站点的试点研究。预先设定的可行性目标是干预完成率和研究保留率>70%(干预后一周完成的结局)。共纳入 23 名癌症住院后出院至 12 家 SNF 的患者及其 21 名照护者。主要结局是可行性和可接受性。在基线和干预后一周收集了探索性的患者和照护者报告结局,包括照护目标。在 6 个月的随访中收集了医疗保健利用情况、死亡率和临终关怀利用情况。在 73 名筛选患者中,35 名(48%)符合条件,23 名(66%)患者及其 21 名照护者入组。18 名(78%)患者完成了干预,10 名(44%)患者及其 13 名(62%)照护者提供了随访结局。患者的平均年龄为 73 岁,19 名(83%)为 III 或 IV 期癌症。照护者的平均年龄为 55 岁。8 名(44%)患者的偏好发生改变,更倾向于接受不太积极的治疗。19 名(83%)患者在干预完成期间或之后不久死亡。来自患者和 SNF 工作人员访谈的定性反馈支持高度可接受性。PCSW 的参与增加了对疾病的理解和患者对预先医疗指令的参与。SNF 工作人员重视增加姑息支持。干预完成率>70%,但由于死亡率高于预期,研究保留率未达到。未来的研究应考虑到高死亡率,并检验 ALIGN 是否能更好地为替代决策者做好准备,并增强 SNF 处理不断变化的照护目标的能力。临床试验注册号:NCT04882111。