James Cook University, McGregor Road, Cairns, Queensland, Australia; Tropical Australian Stinger Research Unit, James Cook University, McGregor Road, Cairns, Queensland, Australia; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine (AITHM), James Cook University, McGregor Road, Cairns, Queensland, Australia.
James Cook University, McGregor Road, Cairns, Queensland, Australia; Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine (AITHM), James Cook University, McGregor Road, Cairns, Queensland, Australia.
Toxicon. 2023 Jan 1;221:106977. doi: 10.1016/j.toxicon.2022.106977. Epub 2022 Nov 19.
Although stonefish (Synanceia spp.) are well-known to harbour a highly noxious defensive venom in their dorsal spines, very little is known about the composition and ecological function of the ichthyocrinotoxins that they secrete onto their epidermis. This study profiled reef (Synanceia verrucosa) and estuarine (Synanceia horrida) stonefish ichthyocrinotoxins via electrophoresis, liquid chromatography, and mass spectrometry to visualise and compare the composition of these toxins between the two species. Stonefish ichthyocrinotoxins were found to be multifarious concoctions that exhibited subtle differences between reef and estuarine species. We speculate that these variations and similarities are driven by the different and similar ecology of these fish species. Further research into the activity of the toxins components is now required to better understand their ecological role.
尽管石鱼（Synanceia spp.）的背刺中含有一种高度有害的防御性毒液，但对于它们分泌到表皮上的鱼泌毒素的组成和生态功能却知之甚少。本研究通过电泳、液相色谱和质谱法对珊瑚礁（Synanceia verrucosa）和河口（Synanceia horrida）石鱼的鱼泌毒素进行了剖析，以观察和比较这两个物种的毒素组成。研究发现，石鱼鱼泌毒素是多种混合物，在珊瑚礁和河口物种之间表现出细微的差异。我们推测，这些差异和相似性是由这些鱼类物种的不同和相似的生态驱动的。现在需要进一步研究毒素成分的活性，以更好地了解它们的生态作用。
