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亚甲蓝联合罗哌卡因肋间神经阻滞在自体肋软骨隆颏术后镇痛中的应用。

Application of methylene blue combined with ropivacaine intercostal nerve block in postoperative analgesia of autologous costal cartilage augmentation rhinoplasty.

机构信息

Department of Anesthesiology, Chongqing Huamei Plastic Surgery Hospital, 400010, Chongqing, China.

Department of Cosmetology, Chongqing Huamei Plastic Surgery Hospital, 400010, Chongqing, China.

出版信息

Anaesthesiologie. 2022 Dec;71(Suppl 2):233-239. doi: 10.1007/s00101-022-01222-8. Epub 2022 Nov 21.

DOI:10.1007/s00101-022-01222-8
PMID:36414741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9763146/
Abstract

OBJECTIVE

To observe the effect of methylene blue combined with ropivacaine intercostal nerve block on postoperative analgesia after autologous costal cartilage augmentation rhinoplasty.

METHODS

In this study 100 female patients who underwent autologous costal cartilage comprehensive augmentation rhinoplasty in Chongqing Huamei Plastic Surgery Hospital from April to November 2021 were randomly divided into an experimental group and a control group, with 50 cases in each group. In the experimental group methylene blue was combined with ropivacaine intercostal nerve block as patient controlled intravenous analgesia (PCIA), and the control group was ropivacaine intercostal nerve block combined with PCIA. The visual analogue scale (VAS) scores of resting and coughing at 6 h (T1), 24 h (T2), 48 h (T3), 72 h (T4) after surgery were recorded and evaluated. At the same time, the number and times of oral analgesics were recorded as well as nausea, vomiting, burning pain and paresthesia.

RESULTS

The VAS scores of the experimental group were lower than those of the control group at all time points. At 6 h, 24 h and 48 h after surgery, the VAS score of the experimental group was lower than that in the control group, but the difference was not statistically significant (P > 0.05). The VAS score of calm 72 h after surgery in the experimental group was significantly lower than that in the control group (P < 0.05). The analgesic effect of the two groups was better when they coughed after surgery. At 6 h after surgery, the VAS score of coughing in the experimental group was lower than that in the control group, but the difference was not statistically significant (P > 0.05); At 24 h, 48 h and 72 h after surgery, the VAS score of the coughing state in the experimental group was significantly lower than that in the control group (P < 0.05).

CONCLUSION

Intercostal nerve block with methylene blue combined with ropivacaine can achieve good postoperative analgesic effects in augmentation rhinoplasty with autologous costal cartilage.

摘要

目的

观察亚甲蓝复合罗哌卡因肋间神经阻滞对自体肋软骨综合隆鼻术后镇痛的影响。

方法

选取 2021 年 4 月至 11 月在重庆华美整形美容医院行自体肋软骨综合隆鼻术的 100 例女性患者,随机分为实验组和对照组,每组 50 例。实验组采用亚甲蓝复合罗哌卡因肋间神经阻滞联合患者自控静脉镇痛(PCIA),对照组采用罗哌卡因肋间神经阻滞联合 PCIA。记录并评估术后 6 h(T1)、24 h(T2)、48 h(T3)、72 h(T4)静息和咳嗽时的视觉模拟评分(VAS),同时记录口服镇痛药的次数和次数,以及恶心、呕吐、烧灼感和感觉异常。

结果

实验组各时间点 VAS 评分均低于对照组。术后 6 h、24 h 和 48 h,实验组 VAS 评分低于对照组,但差异无统计学意义(P>0.05)。术后 72 h 实验组安静时 VAS 评分明显低于对照组(P<0.05)。两组术后咳嗽时镇痛效果均较好。术后 6 h 实验组咳嗽时 VAS 评分低于对照组,但差异无统计学意义(P>0.05);术后 24 h、48 h 和 72 h,实验组咳嗽状态时 VAS 评分明显低于对照组(P<0.05)。

结论

亚甲蓝复合罗哌卡因肋间神经阻滞可在自体肋软骨隆鼻术中获得良好的术后镇痛效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/982c4192ac7f/101_2022_1222_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/2bf3932bfe5d/101_2022_1222_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/b3fb24111d35/101_2022_1222_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/5adfa6515ed5/101_2022_1222_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/982c4192ac7f/101_2022_1222_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/2bf3932bfe5d/101_2022_1222_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/b3fb24111d35/101_2022_1222_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/5adfa6515ed5/101_2022_1222_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6c/9763146/982c4192ac7f/101_2022_1222_Fig4_HTML.jpg

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Biochem Biophys Res Commun. 2021 Feb 19;541:36-42. doi: 10.1016/j.bbrc.2021.01.008. Epub 2021 Jan 16.
2
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J Natl Compr Canc Netw. 2021 Jan 4;19(5):521-527. doi: 10.6004/jnccn.2020.7651. Print 2021 May.
3
Safety of Irradiated Homologous Costal Cartilage Graft in Cleft Rhinoplasty.
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Aesthetic Plast Surg. 2024 Mar;48(5):803-815. doi: 10.1007/s00266-023-03621-7. Epub 2023 Sep 7.
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4
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5
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9
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Aesthet Surg J. 2020 Jul 13;40(8):829-835. doi: 10.1093/asj/sjaa012.
10
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BMC Anesthesiol. 2019 Oct 17;19(1):184. doi: 10.1186/s12871-019-0862-z.