Somanader Deborah S, Brunskill Ian, Perrin Maureen, Barkema Herman Wildrik, Hillier Sean, Hindmarch Suzanne, Weese J Scott, Wright Gerard D, Morris Andrew M
Antimicrobial Stewardship Program, Sinai Health-University Health Network, Toronto, ON, Canada.
Igneum Inc., Toronto, ON, Canada.
Lancet Reg Health Am. 2022 Dec;16:100393. doi: 10.1016/j.lana.2022.100393. Epub 2022 Nov 18.
Antimicrobial Resistance (AMR) causes more than a million deaths globally per year due to infections incurable with currently available antibiotics. Failing to effectively address AMR will have significant negative consequences for Canadians and the Canadian economy. Canada is behind on allocation of required funding and nationally coordinated AMR mitigation strategies relative to other high-income countries. A Pan-Canadian AMR action plan and development of a new governance model is pending. Recent AMR-specific funding commitments are significant but fall short while distribution of funds indicate a siloed approach. Canada could initiate progress towards AMR mitigation through incorporation within the scope of budget allocations intended for COVID-19 recovery and mitigation efforts. We discuss the following components for inclusion: development of infectious disease diagnostics and therapeutics; antimicrobial stewardship interventions in long-term care and Indigenous communities; environmental monitoring of AMR; comprehensive antimicrobial use, and AMR surveillance; and support for capacity-building in low and middle-income countries.
抗微生物药物耐药性(AMR)每年在全球导致超过100万人死亡,原因是目前可用的抗生素无法治愈这些感染。未能有效应对AMR将给加拿大人和加拿大经济带来重大负面影响。与其他高收入国家相比,加拿大在所需资金分配和全国协调的AMR缓解战略方面落后。一项泛加拿大AMR行动计划和新治理模式的制定正在等待中。最近针对AMR的资金承诺数额巨大,但仍有不足,而且资金分配显示出一种各自为政的方式。加拿大可以通过将其纳入旨在应对COVID-19恢复和缓解努力的预算分配范围内,启动AMR缓解方面的进展。我们讨论了以下应纳入的组成部分:传染病诊断和治疗的发展;长期护理和原住民社区的抗菌药物管理干预措施;AMR的环境监测;全面的抗菌药物使用和AMR监测;以及对低收入和中等收入国家能力建设的支持。