Candrawinata Valeska Siulinda, Koerniawan Heru Sutanto, Prasetiyo Patricia Diana, Baskoro Bernard Agung
Faculty of Medicine, Pelita Harapan University, Tangerang, Indonesia.
Department of Surgery, Faculty of Medicine, Pelita Harapan University, Siloam General Hospital, Tangerang, Indonesia.
J Surg Case Rep. 2022 Oct 25;2022(10):rjac470. doi: 10.1093/jscr/rjac470. eCollection 2022 Oct.
Syringocystadenoma papilliferum is a rare, benign hamartomatous neoplasm of skin adnexal originating from pluripotent cells differentiating into either apocrine or eccrine sweat glands. It usually appears at birth, during infancy or puberty and commonly located at head and neck. This case report illustrates a rare occurrence at an atypical anatomical location and unusual onset. In this case report, we report a 20-year-old female with a chief complain of solitary pink-brown color fleshy plaque with soft-medium consistency on her left flank region since the last 7 months. She underwent complete surgical excision and histopathology examination, which confirmed the diagnosis as syringocystadenoma papilliferum without sign of malignancy, with main characteristics histologically include cystic invaginations from the epidermis lined by double layers of epithelial and myoepithelial cells. Despite having benign characteristics, rare transformations to malignancy have been reported. Therefore, complete surgical excision and histopathology examination should be done in suspicion of syringocystadenoma papilliferum.
乳头状汗管囊腺瘤是一种罕见的皮肤附属器良性错构瘤性肿瘤，起源于多能细胞，可分化为顶泌汗腺或小汗腺。它通常在出生时、婴儿期或青春期出现，常见于头颈部。本病例报告展示了其在非典型解剖部位的罕见发生情况及不寻常的发病过程。在本病例报告中，我们报道了一名20岁女性，自7个月前起，其主要诉求为左侧胁腹区域有一个孤立的粉棕色肉质斑块，质地软至中等。她接受了完整的手术切除及组织病理学检查，结果确诊为乳头状汗管囊腺瘤，无恶性迹象，其主要组织学特征包括由双层上皮细胞和肌上皮细胞衬里的表皮囊性内陷。尽管具有良性特征，但已有罕见的恶变报道。因此，怀疑为乳头状汗管囊腺瘤时应进行完整的手术切除及组织病理学检查。
