Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur.
Department of Gastroenterology, All India Institute of Medical Sciences (AIIMS), Jodhpur.
Monaldi Arch Chest Dis. 2022 Nov 25;93(3). doi: 10.4081/monaldi.2022.2418.
Mucormycosis is an opportunistic infection seen in immunocompromised patients or in surgical and trauma settings with Mucorales wound contamination. In immunocompetent people, disseminated mucormycosis is uncommon. To ensure survival, patients with mucormycosis require early diagnosis and aggressive treatment using a multi-modality approach. We present a case of disseminated mucormycosis in an immunocompetent patient who also had pulmonary embolism and gastrointestinal bleeding. A recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, identified retrospectively by a positive IgM against SARS-CoV-2, was the only risk factor present. This report emphasizes the increased risk of mucormycosis and thromboembolic complications following a recent SARS-CoV-2 infection, as well as its successful treatment with medical therapy alone.
毛霉菌病是一种机会性感染,见于免疫功能低下的患者或在外科和创伤环境中存在毛霉属伤口污染的情况下。在免疫功能正常的人群中,播散性毛霉菌病并不常见。为了确保生存,毛霉菌病患者需要早期诊断和采用多模式方法进行积极治疗。我们报告了一例免疫功能正常的患者发生播散性毛霉菌病,同时还患有肺栓塞和胃肠道出血。最近的严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 感染,通过针对 SARS-CoV-2 的 IgM 阳性反应回溯性确定,是唯一存在的危险因素。本报告强调了最近 SARS-CoV-2 感染后毛霉菌病和血栓栓塞并发症的风险增加,以及单独使用药物治疗即可获得成功。