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表现为脂肪瘤的前额结节性汗腺癌:一例病例报告并文献复习

Nodular hidradenocarcinoma of the forehead presenting as a lipoma: A case report with a review of literature.

作者信息

Alshareef Basem H, Ghazzawi Raghad A, Sheikh Ghofran E

机构信息

Department of General Surgery, College of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.

Department of Otorhinolaryngology - Head and Neck Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2022 Dec;101:107795. doi: 10.1016/j.ijscr.2022.107795. Epub 2022 Nov 23.

Abstract

INTRODUCTION

Hidradenocarcinoma is an uncommon slow-growing malignant tumor that originates from sweat glands, it is most seen in the head and neck, and present typically as hard asymptomatic nodule. Diagnosis is confirmed by histopathology and immunohistochemistry, and wide local excision is the mainstay of the treatment. In our study, we discuss the approach and management of this rare disease, with focusing on the importance of histopathology in diagnosing such cases.

PRESENTATION OF CASE

We present a very rare case of a 58-year-old female who presented with painless slow growing forehead swelling for 2 years, with clinical feature suggestive of lipoma. The patient underwent surgical excision, and post-operative histopathological examination of the specimen was consistent with nodular hidradenocarcinoma.

DISCUSSION

Hidradenocarcinoma is a very rare malignant tumor that was first reported in 1954. This tumor was reported to be more common in males, and the incidence increases with age. The origin of hidradenocarcinoma is mostly de novo. The definitive diagnosis requires histopathological examination, and wide local excision is the mainstay of the treatment.

CONCLUSION

Hidradenocarcinoma is a very rare sweat gland malignancy, and the diagnosis can be challenging. In our study, we emphasize the importance of raising the awareness among the surgical oncology society regarding this rare tumor, and we discuss the approach and management of such an uncommon disease, with focusing on the importance of histopathology in diagnosing such cases.

摘要

引言

汗腺癌是一种罕见的生长缓慢的恶性肿瘤,起源于汗腺,多见于头颈部,通常表现为坚硬的无症状结节。通过组织病理学和免疫组织化学确诊,广泛局部切除是主要治疗方法。在我们的研究中,我们讨论了这种罕见疾病的治疗方法和管理,重点关注组织病理学在诊断此类病例中的重要性。

病例介绍

我们报告一例非常罕见的病例,一名58岁女性,前额出现无痛性缓慢生长的肿胀2年,临床特征提示脂肪瘤。患者接受了手术切除,术后标本的组织病理学检查与结节性汗腺癌一致。

讨论

汗腺癌是一种非常罕见的恶性肿瘤,于1954年首次报道。据报道,这种肿瘤在男性中更为常见,发病率随年龄增长而增加。汗腺癌大多为原发性。明确诊断需要组织病理学检查,广泛局部切除是主要治疗方法。

结论

汗腺癌是一种非常罕见的汗腺恶性肿瘤,诊断可能具有挑战性。在我们的研究中,我们强调提高外科肿瘤学界对这种罕见肿瘤认识的重要性,并讨论了这种罕见疾病的治疗方法和管理,重点关注组织病理学在诊断此类病例中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccd8/9685281/240da6e40373/gr1.jpg

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