Uchida Tsuyoshi, Matsubara Hirochika, Muto Mamoru, Sugimura Aya, Onuki Yuichiro, Nakajima Hiroyuki
Department of Thoracic Surgery, Yamanashi University, Shimokato 1110, Chuo, Yamanashi, Japan.
Department of Thoracic Surgery, Yamanashi University, Shimokato 1110, Chuo, Yamanashi, Japan.
Int J Surg Case Rep. 2022 Dec;101:107776. doi: 10.1016/j.ijscr.2022.107776. Epub 2022 Nov 13.
Pulmonary chondroma, a component of Carney's triad, is commonly unilateral and multiple, and progresses slowly. Herein, we report a case of a chondrogenic tumour that grew and proliferated during follow-up.
A female patient in her 20s presenting with a cough was found to have a 1.4-cm nodule in the left lung on computed tomography (CT). After 18 months' follow-up, CT revealed that the original nodule had increased to 2.2 cm, and a new 1.3-cm nodule had appeared. She was then referred to our hospital and underwent a robot-assisted lower lobectomy of the left lung. The tumour was diagnosed as a chondrogenic tumour. She had no problems after the surgery or during follow-up; other signs of the Carney's triad were ruled out. Twenty-six months postoperatively, there was no evidence of recurrence.
One report suggests that the growth of pulmonary chondroma is slow, but the present case showed an increase in both the size and number of tumours within 2 years without any symptoms. The chondroma did not recur after the surgery, though her pulmonary tumours had grown and proliferated rapidly. Furthermore, it has been reported that an average of 8.4 years is needed for another sign of Carney's triad to appear; therefore, careful follow-up should be continued.
This report suggests that pulmonary chondroma can grow and proliferate rapidly and asymptomatically, and can be controlled by complete resection.
肺软骨瘤是卡尼三联征的一个组成部分，通常为单侧且多发，生长缓慢。在此，我们报告一例软骨源性肿瘤在随访期间生长和增殖的病例。
一名20多岁的女性患者因咳嗽就诊，计算机断层扫描（CT）发现左肺有一个1.4厘米的结节。经过18个月的随访，CT显示原结节增大至2.2厘米，并且出现了一个新的1.3厘米结节。随后她被转诊至我院，接受了机器人辅助下的左肺下叶切除术。肿瘤被诊断为软骨源性肿瘤。术后及随访期间她均无问题；卡尼三联征的其他体征被排除。术后26个月，没有复发迹象。
一份报告表明肺软骨瘤生长缓慢，但本病例显示在2年内肿瘤大小和数量均增加且无任何症状。尽管她的肺部肿瘤生长迅速且增殖，但软骨瘤术后未复发。此外，据报道卡尼三联征的另一个体征平均需要8.4年才会出现；因此，应继续进行仔细随访。
本报告表明肺软骨瘤可迅速且无症状地生长和增殖，并且可通过完整切除得到控制。
