Department of Obstetrics and Gynecology, University of Gothenburg, Gothenburg, Sweden.
Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Transplantation. 2022 Dec 1;106(12):2271-2274. doi: 10.1097/TP.0000000000004188. Epub 2022 Nov 22.
Uterus transplantation (UTx) is currently the only available treatment for absolute uterine factor infertility. The International Society of Uterus Transplantation (ISUTx) was formally founded in 2017 and joined the Transplantation Society as a formal section in 2021. The Third International Congress of the ISUTx was held in Tübingen, Germany, in October 2021, as a hybrid meeting, attended virtually by about 450 delegates and in person by 35 delegates. This report summarizes the Tübingen meeting and complementary topics of relevance presented at the Second ISUTx state-of-the-art webinar meeting, held in Prague, in October 2020. Main topics covered included surgical considerations, including dissection of veins in living donors and the pros and cons of minimally invasive surgery; managing immune risks; UTx during the COVID-19 pandemic; lessons learnt in the areas of imaging and cytomegalovirus infection; long-term psychological outcomes; opportunities to increase organ availability; and new horizons in UTx, including potential reuse of transplants and the utilization of robotic approaches. Implementation of an International UTx Registry was discussed and considered crucial to assure quality, safety, and further progress in UTx. Attempts made thus far have been promising.
子宫移植(UTx)目前是治疗绝对子宫因素不孕的唯一可行方法。国际子宫移植协会(ISUTx)于 2017 年正式成立,并于 2021 年作为正式分会加入移植协会。第三届国际 ISUTx 大会于 2021 年 10 月在德国图宾根举行,采用线上和线下相结合的方式,约有 450 名代表线上参会,35 名代表现场参会。本报告总结了在德国图宾根举行的会议和在 2020 年 10 月于布拉格举行的第二届 ISUTx 最新网络研讨会会议上提出的相关补充议题。主要涵盖的议题包括手术方面的考虑,包括活体供者静脉的解剖以及微创手术的优缺点;免疫风险的管理;新冠疫情期间的 UTx;在影像学和巨细胞病毒感染领域的经验教训;长期心理结果;增加器官供应的机会;以及 UTx 的新领域,包括移植的潜在再利用和机器人方法的应用。会上还讨论了建立国际 UTx 注册系统的问题,认为这对于确保 UTx 的质量、安全性和进一步发展至关重要。迄今为止所做的努力是有希望的。