Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei 238000, China; Anhui Psychiatric Center, Anhui Medical University, Hefei 238000, China.
Anhui Mental Health Center, Hefei 230022, China.
J Affect Disord. 2023 Feb 15;323:40-45. doi: 10.1016/j.jad.2022.11.054. Epub 2022 Nov 24.
Seasonal patterns exist in many disorders and even serve as potential drivers of some disorders, but in schizophrenia and affective disorders, there is no uniform conclusion on the seasonal pattern.
A total of 100,621 inpatients were surveyed in this study over 16 years, and 21,668 inpatients were ultimately included in the count after standard exclusion criteria were applied.
There was an uneven seasonal distribution of mental illness admissions (χ2 = 48.299, df = 18, P < .001). The peak of schizophrenia admissions occurred in the winter and the trough in the spring (52.6 % vs 50 %, P < .05). The peaks for depression and bipolar disorder were in the fall and spring, respectively, while the troughs were in the winter and fall, respectively (24.7 % vs 21.7 %, P < .05; 15.2 % vs 13.2 %, P < .05). Admissions for childhood mood disorders peaked in the fall (P < .05). We also found that the length of stay was also correlated with the season of admission, and that this seasonal fluctuation was not consistent across male and female populations.
To avoid the effect of repeated hospitalizations, we maintained a registry of each patient's first admission only, which also resulted in our inability to explore the seasonal pattern of each disease recurrence at the individual level.
We found that the seasonal distribution of psychiatric admissions was not uniform. And there was also an uneven seasonal distribution of length of stay for patients admitted in different seasons. This may imply that certain environmental factors that vary with the seasons are potential drivers of mental illness.
季节性模式存在于许多疾病中，甚至可能成为某些疾病的潜在驱动因素，但在精神分裂症和情感障碍中，对于季节性模式尚无统一结论。
本研究共调查了 16 年期间的 100621 名住院患者，经过标准排除标准后，最终纳入了 21668 名住院患者进行计数。
精神疾病住院患者的季节性分布不均匀（χ2=48.299，df=18，P<.001）。精神分裂症住院人数的高峰出现在冬季，低谷出现在春季（52.6%比 50%，P<.05）。抑郁症和双相情感障碍的高峰分别出现在秋季和春季，而低谷分别出现在冬季和秋季（24.7%比 21.7%，P<.05；15.2%比 13.2%，P<.05）。儿童情绪障碍的住院人数在秋季达到高峰（P<.05）。我们还发现，住院时间也与入院季节相关，而且这种季节性波动在男女群体中并不一致。
为避免重复住院的影响，我们仅保留每位患者首次住院的记录，这也导致我们无法在个体水平上探索每种疾病复发的季节性模式。
我们发现精神科住院患者的季节性分布并不均匀。不同季节入院患者的住院时间也存在季节性分布不均的情况。这可能意味着某些随季节变化的环境因素是精神疾病的潜在驱动因素。
