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院外心脏骤停患者长期生存的院前预测因素。

Pre-hospital predictors of long-term survival from out-of-hospital cardiac arrest.

机构信息

College of Public Health, Medical and Veterinary Sciences, James Cook University, Angus Park Drive, Douglas 4811, Queensland, Australia; Queensland Ambulance Service, GPO Box 1425, Brisbane 4001, Queensland, Australia.

College of Public Health, Medical and Veterinary Sciences, James Cook University, Angus Park Drive, Douglas 4811, Queensland, Australia.

出版信息

Australas Emerg Care. 2023 Jun;26(2):184-192. doi: 10.1016/j.auec.2022.10.006. Epub 2022 Nov 24.

Abstract

OBJECTIVE

To identify predictors of longer-term outcomes from adult out-of-hospital cardiac arrest of presumed cardiac aetiology.

METHODS

In this retrospective cohort study, three large routinely collected databases were linked: 1)QAS Out-of-Hospital Cardiac (OHCA) Registry; 2)Queensland Hospital Admitted Patient Data Collection; and 3)Queensland Registrar General Death Registry. Participants were adult (18years+) residents of Queensland, who suffered an OHCA of presumed cardiac aetiology and had resuscitation attempted by QAS paramedics between 2002 and 2014. Four mutually exclusive outcomes were analysed: 1) No pre-hospital return of spontaneous circulation (ROSC) sustained to the Emergency Department (ED) or ROSC in ED; 2) Survival< 30 days (Pre-hospital ROSC sustained to ED or ROSC in ED but death within 30 days; 3) survival between 30 and 364 days; and 4) survival to 365 + days. Multinomial logistic regression was used to calculate odds ratios and 95 % confidence intervals.

RESULTS

Variables significantly predictive of survival to 365 + days after adjusting for all measured confounders are: an initial shockable rhythm; bystander witnessed events with bystander CPR; paramedic witnessed events; intubation placement; time of day (midday-2.59 pm); and attendance by Critical Care Paramedic (CCP).

CONCLUSION

From a service provision perspective, attendance of a CCP at an OHCA may be an important factor to achieve preferred long-term outcomes. Enhanced experience, exposure and expertise, together with extended clinical practice, may explain this finding.

摘要

目的

确定成人院外心脏骤停(OHCA)推定心源性病因的长期预后预测因素。

方法

在这项回顾性队列研究中,将三个大型常规收集数据库进行了链接:1)QAS 院外心脏(OHCA)登记处;2)昆士兰州住院患者数据采集;3)昆士兰州登记总署死亡登记处。参与者为昆士兰州的成年(18 岁+)居民,他们在 2002 年至 2014 年间经历了推定心源性病因的 OHCA,并有 QAS 护理人员进行复苏。分析了四个互斥的结局:1)没有院前自主循环(ROSC)恢复到急诊科(ED)或 ED 中的 ROSC;2)存活时间<30 天(ED 中持续存在院前 ROSC 或 ED 中的 ROSC,但在 30 天内死亡);3)存活时间为 30 至 364 天;4)存活至 365+天。使用多变量逻辑回归计算优势比和 95%置信区间。

结果

在校正所有测量混杂因素后,对存活至 365+天后有显著预测意义的变量为:初始可除颤节律;旁观者见证事件伴旁观者心肺复苏术(CPR);护理人员见证事件;插管放置;时间(中午-下午 2.59 点);以及重症护理护理人员(CCP)的出勤。

结论

从服务提供的角度来看,CCP 参加 OHCA 可能是实现首选长期结局的重要因素。增强的经验、暴露和专业知识,以及扩展的临床实践,可能解释了这一发现。

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