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在尸体供体小儿肝移植中,用供体肠系膜上动脉行右肝动脉显微外科重建。

Microsurgical replacement of the right hepatic artery with the donor superior mesenteric artery in cadaveric donor pediatric liver transplantation.

机构信息

Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Liver Transplant Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Pediatr Surg Int. 2022 Nov 28;39(1):13. doi: 10.1007/s00383-022-05281-1.

DOI:10.1007/s00383-022-05281-1
PMID:36441295
Abstract

PURPOSE

To present our experience of using the pediatric donor superior mesenteric artery (SMA) as the interpositioning vessel to reconstruct the hepatic artery in pediatric deceased donor liver transplantation.

METHODS

Pediatric patients who received pediatric deceased donor livers from December 2019 to June 2021 were enrolled.

RESULTS

A total of 43 pediatric recipients received pediatric deceased donor livers during the study period. Thirty-four (79.1%) pediatric donors had normal hepatic artery anatomy, while nine (20.9%) showed variant anatomies. The SMAs of the pediatric donors were interposed in the latter eight cases. The anastomosis between the donor distal SMA and the donor celiac trunk artery (CTA) was initially performed in the back-table period, after which the other anastomosis between the donor proximal SMA and recipient CHA was performed. Only one case showed HAT occurrence (incidence rate, 2.3%). However, no arterial complications occurred in pediatric recipients with donor grafts that showed the variation of RHA replacement from the SMA and had undergone usage of the donor's SMA as an interpositioning vessel.

CONCLUSIONS

In pediatric deceased donor liver transplantation, the use of SMA as an interpositioning medium can solve the problems related to a tiny caliber and anatomical variations of the donor hepatic artery.

摘要

目的

介绍我们在小儿尸体肝移植中使用小儿供体肠系膜上动脉(SMA)作为桥血管重建肝动脉的经验。

方法

纳入 2019 年 12 月至 2021 年 6 月期间接受小儿尸体供肝的患儿。

结果

研究期间,共有 43 名小儿受体接受了小儿尸体供肝。34 例(79.1%)小儿供体肝动脉解剖正常,9 例(20.9%)显示变异解剖。后 8 例将 SMA 作为桥血管进行重建。供体远端 SMA 与供体腹腔干动脉(CTA)的吻合在离体期间完成,然后进行供体近端 SMA 与受体 CHA 的另一次吻合。仅 1 例发生 HAT(发生率 2.3%)。然而,对于因 RHA 由 SMA 替代而出现变异且使用供体 SMA 作为桥血管的供体肝移植患儿,未发生动脉并发症。

结论

在小儿尸体肝移植中,使用 SMA 作为桥接介质可以解决供体肝动脉口径小和解剖变异的问题。

相似文献

1
Microsurgical replacement of the right hepatic artery with the donor superior mesenteric artery in cadaveric donor pediatric liver transplantation.在尸体供体小儿肝移植中,用供体肠系膜上动脉行右肝动脉显微外科重建。
Pediatr Surg Int. 2022 Nov 28;39(1):13. doi: 10.1007/s00383-022-05281-1.
2
[Hepatic arterial reconstruction and complications management in adult-to-adult living donor liver transplantation].[成人活体肝移植中肝动脉重建及并发症处理]
Zhonghua Wai Ke Za Zhi. 2008 Feb 1;46(3):166-9.
3
Hepatic artery reconstruction with interposition of donor's right gastroepiploic artery graft in pediatric living donor liver transplantation for metabolic disease.在儿童活体供肝肝移植治疗代谢性疾病中,采用供体胃网膜右动脉移植进行肝动脉重建。
Pediatr Transplant. 2019 Jun;23(4):e13418. doi: 10.1111/petr.13418. Epub 2019 Apr 23.
4
Early Hepatic Artery Thrombosis After Liver Transplantation: What is the Impact of the Arterial Reconstruction Type?肝移植术后早期肝动脉血栓形成:动脉重建类型有何影响?
World J Surg. 2017 Aug;41(8):2101-2110. doi: 10.1007/s00268-017-3989-4.
5
Back-table arterial reconstructions in liver transplantation: single-center experience.肝移植中的后台动脉重建:单中心经验
Transplant Proc. 2005 Jul-Aug;37(6):2587-8. doi: 10.1016/j.transproceed.2005.06.058.
6
Microvascular Hepatic Artery Anastomosis in Pediatric Living Donor Liver Transplantation: 73 Consecutive Cases Performed by a Single Surgeon.小儿活体肝移植中肝动脉的微血管吻合:由一位外科医生完成的 73 例连续病例。
Plast Reconstr Surg. 2018 Dec;142(6):1609-1619. doi: 10.1097/PRS.0000000000005044.
7
Use of an aberrant right hepatic artery arising from the superior mesenteric artery of the recipient for arterial reconstruction in liver transplantation.利用受体肠系膜上动脉发出的变异右肝动脉进行肝移植中的动脉重建。
Ann Transplant. 2010 Oct-Dec;15(4):44-8.
8
Microsurgical Hepatic Artery Reconstruction in Deceased Donor Liver Transplantation for Reduced Arterial Complications.在减少动脉并发症的情况下,进行尸体供肝移植中的显微外科肝动脉重建。
Transplant Proc. 2021 Jun;53(5):1645-1652. doi: 10.1016/j.transproceed.2021.04.009. Epub 2021 May 14.
9
Hepatic artery thrombosis in infants. A comparison of whole livers, reduced-size grafts, and grafts from living-related donors.婴儿肝动脉血栓形成。全肝、减体积移植物及活体亲属供体移植物的比较。
Transplantation. 1992 Feb;53(2):396-9. doi: 10.1097/00007890-199202010-00025.
10
[Reconstruction of hepatic artery in adult to adult living donor liver transplantation in 104 patients].[104例成人对成人活体肝移植中肝动脉重建]
Zhonghua Yi Xue Za Zhi. 2009 Jun 9;89(22):1533-5.

本文引用的文献

1
Risk factors of hepatic artery thrombosis in pediatric deceased donor liver transplantation.小儿脑死亡供体肝移植中肝动脉血栓形成的危险因素
Pediatr Surg Int. 2019 Aug;35(8):853-859. doi: 10.1007/s00383-019-04500-6. Epub 2019 Jun 15.
2
Hepatic artery reconstruction with interposition of donor's right gastroepiploic artery graft in pediatric living donor liver transplantation for metabolic disease.在儿童活体供肝肝移植治疗代谢性疾病中,采用供体胃网膜右动脉移植进行肝动脉重建。
Pediatr Transplant. 2019 Jun;23(4):e13418. doi: 10.1111/petr.13418. Epub 2019 Apr 23.
3
Long-term outcome of liver transplantation in childhood: A study of 20-year survivors.
儿童肝移植的长期预后:20 年生存者研究。
Am J Transplant. 2018 Jul;18(7):1680-1689. doi: 10.1111/ajt.14626. Epub 2018 Jan 12.
4
Long-term results of urgent revascularization for hepatic artery thrombosis after pediatric liver transplantation.小儿肝移植术后肝动脉血栓形成行紧急血运重建的长期疗效。
Liver Transpl. 2010 Jul;16(7):847-55. doi: 10.1002/lt.22063.
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The management of an accessory or replaced right hepatic artery during multiorgan retrieval: results of an angiographic study.多器官获取时副肝右动脉或替代肝右动脉的管理:血管造影研究结果。
Liver Transpl. 2010 Jun;16(6):742-7. doi: 10.1002/lt.22075.
6
Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors.肝移植术后早期肝动脉血栓形成:发病率、结局及危险因素的系统评价
Am J Transplant. 2009 Apr;9(4):746-57. doi: 10.1111/j.1600-6143.2008.02541.x. Epub 2009 Mar 2.
7
CT angiography for delineation of celiac and superior mesenteric artery variants in patients undergoing hepatobiliary and pancreatic surgery.CT血管造影术用于在接受肝胆胰手术的患者中描绘腹腔干和肠系膜上动脉变异。
AJR Am J Roentgenol. 2007 Jul;189(1):W13-9. doi: 10.2214/AJR.04.1374.
8
A new reconstruction of the accessory donor right hepatic artery with interposition of the SMA in liver transplantation.肝移植中一种采用肠系膜上动脉间置的副供体右肝动脉新重建方法。
Surgery. 2006 Nov;140(5):835. doi: 10.1016/j.surg.2006.03.010. Epub 2006 Jul 28.
9
Living donor liver transplantation for biliary atresia: a single-center experience with first 100 cases.活体供肝肝移植治疗胆道闭锁:单中心100例首例经验
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10
Vascular reconstruction and complications in living donor liver transplantation in infants weighing less than 6 kilograms: the Kyoto experience.体重小于6千克婴儿活体肝移植中的血管重建与并发症:京都经验
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