Pontarotti Gaëlle
Institut d'histoire et de philosophie des sciences et des techniques (IHPST), université Paris 1 Panthéon-Sorbonne, 13 rue du Four, Paris 75006, France.
Med Sci (Paris). 2022 Nov;38(11):936-940. doi: 10.1051/medsci/2022147. Epub 2022 Nov 30.
The extension of biological inheritance beyond gene-centrism is at the center of many debates in evolutionary biology, but it has been relatively ignored in the field of biomedicine. The purpose of this prospective paper is to highlight the potential impact of a new vision of inheritance on medical theory, notably on the concept of hereditary disease. It is also to underline some related practical and social issues.
生物遗传的扩展超越了基因中心论,这是进化生物学中诸多争论的核心,但在生物医学领域却相对被忽视。这篇前瞻性论文的目的是强调遗传新视角对医学理论的潜在影响,尤其是对遗传性疾病概念的影响。同时也要强调一些相关的实际和社会问题。