Majd Ali, Lim Catherine, Zloty David
Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
Dermatol Surg. 2022 Dec 1;48(12):1289-1293. doi: 10.1097/DSS.0000000000003625.
A common concern among patients following Mohs micrographic surgery (MMS) is scar appearance and residual erythema. However, few studies have quantitatively compared scar erythema between different suture materials.
To quantify erythema intensity (EI) associated with use of percutaneous nylon, irradiated polyglactin-910 (IPG) and fast-absorbing gut (FG) sutures on facial sites.
After undergoing MMS, 210 patients were randomized to one of 2 groups. Patients in the first group (n = 105) had their defects repaired half with continuous IPG sutures and the other half with nylon sutures; the second group (n = 105) received IPG and FG sutures. Standardized photographs of scars were taken at 1 week, 2 months, and 6 months postoperatively and computer-assisted image analysis was used to quantify EI.
The average EI was comparable between all 3 suture materials at 1 week, 2 months, and 6 months. From 1 week to 2 months, EI in nylon, IPG, and FG sutures decreased by 24.8%, 12.8%, and 17.9% (p < .05), respectively. There was no statistically significant difference in EI among suture types between 2 and 6 months.
Erythema decreased significantly during early scar maturation in all groups and was comparable between all suture materials at 1 week, 2 months, and 6 months.
莫氏显微外科手术（MMS）后患者普遍关心的问题是瘢痕外观和残余红斑。然而，很少有研究对不同缝合材料之间的瘢痕红斑进行定量比较。
量化面部使用经皮尼龙线、辐照聚乙醇酸-910（IPG）和快吸收肠线（FG）缝合后红斑强度（EI）。
210例接受MMS的患者被随机分为2组。第一组（n = 105）患者的缺损一半用连续IPG缝线修复，另一半用尼龙线修复；第二组（n = 105）接受IPG和FG缝线。术后1周、2个月和6个月拍摄瘢痕的标准化照片，并使用计算机辅助图像分析来量化EI。
在1周、2个月和6个月时，所有3种缝合材料的平均EI相当。从1周到2个月，尼龙线、IPG线和FG线的EI分别下降了24.8%、12.8%和17.9%（p < .05）。在2至6个月期间，不同缝合类型之间的EI没有统计学显著差异。
在所有组中，早期瘢痕成熟过程中红斑显著减少，在1周、2个月和6个月时，所有缝合材料之间的红斑情况相当。
