Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Bakircay University, İzmir, Turkey.
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.
Ir J Med Sci. 2023 Oct;192(5):2379-2386. doi: 10.1007/s11845-022-03237-x. Epub 2022 Dec 1.
Evaluation of activities of daily living (ADL) and functional exercise capacity in patients with multiple sclerosis (pwMS) is crucial in demonstrating the effectiveness of interventions.
To investigate the reliability and validity of the Glittre ADL Test in pwMS.
Twenty-five pwMS and 26 healthy adults were included in this methodological study. The Glittre ADL Test was applied. Six-Minute Walk Test (6MWT) and Nottingham Extended Activities of Daily Living Index (NEADL) were applied for concurrent validity. Expanded Disability Status Scale (EDSS), Fatigue Severity Scale (FSS), Mini Balance Evaluation Systems Test (Mini BESTest), Multiple Sclerosis Quality of Life Scale-54 (MSQoL-54), and Five Times Sit-to-Stand Test (5 STST) were applied for construct validity. The Glittre ADL Test was repeated after 3-6 days for test-retest reliability.
The test-retest reliability of the Glittre ADL Test was excellent (ICC = 0.941). There was strong correlation of the Glittre ADL Test with 6MWT (rho = - 0.710, p < 0.001), NEADL (rho = - 0.841, p < 0.001), EDSS, (rho = 0.836, p = < 0.001), Mini BESTest (rho = 0.792, p < 0.001), and 5 STST scores (rho = 0.720, p < 0.001). There was a moderate correlation between the Glittre ADL Test and the physical health sub-item score of the MSQoL-54 (rho = - 0.591, p = 0.002). No correlation was found between the Glittre ADL Test and FSS (rho = 0.348, p = 0.096). There was a difference in the Glittre ADL Test results between the pwMS and the healthy adults (p = 0.001).
The Glittre ADL Test has excellent reliability and strong construct and criterion validity for assessing functional exercise capacity and ADL in fully ambulatory pwMS.
TRN: NCT04182269.
评估多发性硬化症（pwMS）患者的日常生活活动（ADL）和功能运动能力对于证明干预措施的有效性至关重要。
调查 Glittre ADL 测试在 pwMS 中的可靠性和有效性。
本方法学研究纳入了 25 名 pwMS 和 26 名健康成年人。应用 Glittre ADL 测试。同时应用 6 分钟步行测试（6MWT）和诺丁汉扩展日常生活活动指数（NEADL）进行同期有效性评估。应用扩展残疾状况量表（EDSS）、疲劳严重程度量表（FSS）、简易平衡评估系统测试（Mini BESTest）、多发性硬化生活质量量表-54（MSQoL-54）和 5 次坐立测试（5 STST）进行结构有效性评估。在 3-6 天后重复 Glittre ADL 测试以评估测试-重测信度。
Glittre ADL 测试的重测信度极好（ICC=0.941）。Glittre ADL 测试与 6MWT（rho=-0.710，p<0.001）、NEADL（rho=-0.841，p<0.001）、EDSS（rho=0.836，p<0.001）、Mini BESTest（rho=0.792，p<0.001）和 5 STST 评分（rho=0.720，p<0.001）均具有强相关性。Glittre ADL 测试与 MSQoL-54 的身体健康子项评分（rho=-0.591，p=0.002）之间具有中度相关性。Glittre ADL 测试与 FSS 之间无相关性（rho=0.348，p=0.096）。pwMS 与健康成年人的 Glittre ADL 测试结果存在差异（p=0.001）。
Glittre ADL 测试在评估完全活动的 pwMS 的功能运动能力和 ADL 方面具有极好的可靠性以及较强的结构和标准效度。
TRN：NCT04182269。
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