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一名患有继发性红细胞增多症的年轻男性的急性肢体缺血：病例报告。

Acute limb ischaemia in a young male with secondary polycythaemia: A case report.

作者信息

Kam Cheuk Tung, Ahmed Syed, Milligan Fintan, Sip Benjamin

机构信息

The Royal Victoria Hospital, Belfast Health and Social Care Trust, 274 Grosvenor Road, Belfast, BT12 6BA, United Kingdom.

出版信息

Radiol Case Rep. 2022 Nov 28;18(2):596-598. doi: 10.1016/j.radcr.2022.11.001. eCollection 2023 Feb.

DOI:10.1016/j.radcr.2022.11.001
PMID:36452889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9703451/
Abstract

Acute limb ischemia is a life and limb-threatening pathology rarely observed in young populations. One of the uncommon causes includes hypercoagulable state which can occur in secondary polycythemia leading to an abnormal increase in the erythrocyte mass. We present a rare case of Rutherford type 2A acute limb ischemia in a 36-year-old male patient with a background of secondary polycythemia who presented with severe pain and neurological deficits in his left lower limb. Acute limb ischemia is a surgical emergency that is important for clinicians to have a low threshold of suspicion of this life and limb-threatening condition due to the diverse and potentially atypical causes.

摘要

急性肢体缺血是一种危及生命和肢体的病理状况，在年轻人群中很少见。其中一种不常见的病因是高凝状态，可发生于继发性红细胞增多症，导致红细胞数量异常增加。我们报告一例罕见病例，一名36岁男性患者，有继发性红细胞增多症病史，出现卢瑟福2A型急性肢体缺血，表现为左下肢严重疼痛和神经功能缺损。急性肢体缺血是一种外科急症，由于病因多样且可能不典型，临床医生对这种危及生命和肢体的疾病保持较低的怀疑阈值很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/3e057fc8671d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/8c897f35a41e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/27ce22bf5b25/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/6ed694f2bde8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/0f6ca7f73f12/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/3e057fc8671d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/8c897f35a41e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/27ce22bf5b25/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/6ed694f2bde8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/0f6ca7f73f12/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cac/9703451/3e057fc8671d/gr5.jpg

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本文引用的文献

1
Acute Limb Ischemia in the Young: A Rare Case of Essential Thrombocytosis.青年急性肢体缺血：原发性血小板增多症的罕见病例
Case Rep Cardiol. 2021 Nov 20;2021:2563578. doi: 10.1155/2021/2563578. eCollection 2021.
2
Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors.慢性阻塞性肺疾病中的继发性红细胞增多症：患病率和危险因素。
BMC Pulm Med. 2021 Jul 14;21(1):235. doi: 10.1186/s12890-021-01585-5.
3
Investigation and Management of Erythrocytosis.红细胞增多症的调查与管理
Curr Hematol Malig Rep. 2016 Oct;11(5):342-7. doi: 10.1007/s11899-016-0334-1.
4
Acute Limb Ischemia: A Case Report and Literature Review.急性肢体缺血：病例报告与文献综述
J Emerg Med. 2015 Dec;49(6):1011-7. doi: 10.1016/j.jemermed.2015.03.008. Epub 2015 Jun 19.
5
Hypoxemia in patients with COPD: cause, effects, and disease progression.慢性阻塞性肺疾病患者的低氧血症：病因、影响和疾病进展。
Int J Chron Obstruct Pulmon Dis. 2011;6:199-208. doi: 10.2147/COPD.S10611. Epub 2011 Mar 14.
6
Haemoglobin level and its clinical impact in a cohort of patients with COPD.慢性阻塞性肺疾病（COPD）患者队列中的血红蛋白水平及其临床影响
Eur Respir J. 2007 May;29(5):923-9. doi: 10.1183/09031936.00137106. Epub 2007 Jan 24.
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Efficacy and safety of low-dose aspirin in polycythemia vera.低剂量阿司匹林治疗真性红细胞增多症的疗效与安全性
N Engl J Med. 2004 Jan 8;350(2):114-24. doi: 10.1056/NEJMoa035572.