Department of Psychiatry, Ningbo Kangning Hospital, Affiliated Mental Health Center of Ningbo University, Ningbo, Zhejiang, China.
Taizhou Second People's Hospital, Taizhou, Zhejiang, China.
J Clin Sleep Med. 2022 Dec 1;18(12):2871-2874. doi: 10.5664/jcsm.10272.
Long-term insomnia affects the normal life and work of individuals and increases the risk of various health problems, including mental illness. Therefore, there is an urgent need for an efficient and safe treatment for improving sleep. In this study, we report the case a 52-year-old woman who received repetitive transcranial magnetic stimulation (rTMS) combined with transcranial direct current stimulation (tDCS) after agreeing to publish her case. In order to evaluate the quality of sleep and the stability of emotional symptoms, clinical evaluations were conducted at baseline, after 10 treatment sessions, after 20 treatment sessions, and 1 month after the end of treatment. After completing rTMS combined with tDCS, the patient showed an overall clinical improvement, with clinical changes mainly observed in the Pittsburgh Sleep Quality Index, Hamilton Depression Scale, Hamilton Anxiety Scale scores and polysomnography, and this improvement was maintained 1 month after the intervention. This case provides the first evidence for the feasibility, tolerability, and safety of combined rTMS and tDCS in a patient with chronic insomnia.
Registry: Chinese Clinical Trial Registry; Name: Clinical study of repetitive transcranial magnetic stimulation combined with transcranial direct current stimulation in the treatment of chronic insomnia; URL: http://www.chictr.org.cn/edit.aspx?pid=57440&htm=4; Identifier: ChiCTR ChiCTR2100052681.
Zhou Q, Liu Z, Zhao S, et al. Transcranial magnetic stimulation combined with transcranial direct current stimulation in patients with chronic insomnia: a case report. . 2022;18(12):2871-2873.
中文译文:
标题:经颅磁刺激联合经颅直流电刺激治疗慢性失眠 1 例报告
摘要:
长期失眠影响个体的正常生活和工作,并增加各种健康问题的风险,包括精神疾病。因此,迫切需要一种有效的、安全的治疗方法来改善睡眠。本研究报告了 1 例 52 岁女性患者,在同意发表其病例后,接受重复经颅磁刺激(rTMS)联合经颅直流电刺激(tDCS)治疗。为了评估睡眠质量和情绪症状的稳定性,在基线时、治疗 10 次后、治疗 20 次后和治疗结束后 1 个月进行临床评估。
完成 rTMS 联合 tDCS 治疗后,患者整体临床改善,匹兹堡睡眠质量指数、汉密尔顿抑郁量表、汉密尔顿焦虑量表评分和多导睡眠图的临床变化主要观察到,这种改善在干预后 1 个月仍持续。
本病例为慢性失眠患者联合 rTMS 和 tDCS 的可行性、耐受性和安全性提供了首例证据。
中国临床试验注册中心;名称:重复经颅磁刺激联合经颅直流电刺激治疗慢性失眠的临床研究;网址:http://www.chictr.org.cn/edit.aspx?pid=57440&htm=4;标识符:ChiCTR ChiCTR2100052681。