Alsaaod M, Schmid R M, Zwahlen N, Soto S, Wildi N, Seuberlich T, Steiner A
Wiederkäuerklinik, Vetsuisse-Fakultät, Universität Bern.
Institut für Tierpathologie, Vetsuisse-Fakultät, Universität Bern.
Schweiz Arch Tierheilkd. 2022 Dec;164(12):851-859. doi: 10.17236/sat00378.
Contagious ovine digital dermatitis (CODD) is an emerging infectious foot disease in sheep. To date, CODD has been described in Great Britain, Ireland, Sweden and Germany and now in Switzerland for the first time. Unlike foot rot, the CODD lesions do not spread from the interdigital space, but usually begin at the dorsal/abaxial coronary band. The changes can spread to the hoof wall and the sole and finally can lead to exungulation, similar to foot rot. Treponema spp. are often found in CODD lesions analogous to digital dermatitis (Mortellaro's disease) in cattle. Involvement of Dichelobacter nodosus (D. nodosus) is considered a risk factor, but the presence of the bacterium is not mandatory. In February 2022, ulcerative lesions in the dorso-axial coronary band area were noticed on both claws of the left forelimb in an ewe. Histology of the biopsy showed hyperkeratosis and erosion with exocytosis and crust formation. Treponema spp. PCR and fluorescence in situ hybridization (FISH) were positive for Treponema phylotype 1 (PT1). In addition, D. nodosus and Porphyromonas levii could be detected in the biopsy using PCR. A single local application of chlortetracycline spray led to clinical healing within two weeks, no recurrence was seen within the following two months. Three control sheep, which were kept together with the diseased sheep, did not show any clinical signs of CODD. Treponema spp could not be found in interdigital and coronary band biopsies by PCR or FISH. This is the first description of CODD in Switzerland and aims to sensitize veterinarians to CODD as a differential diagnosis for foot diseases in sheep.
传染性绵羊趾间皮炎（CODD）是一种新出现的绵羊足部传染病。迄今为止，英国、爱尔兰、瑞典和德国都有CODD的相关报道，现在瑞士首次发现了该病。与腐蹄病不同，CODD病变并非从趾间间隙扩散，而是通常始于背侧/远轴冠状带。病变可蔓延至蹄壁和蹄底，最终可能导致蹄脱落，这与腐蹄病类似。密螺旋体属细菌常在CODD病变中被发现，类似于牛的趾间皮炎（莫泰拉罗病）。结节类杆菌（D. nodosus）的感染被认为是一个风险因素，但该细菌的存在并非必需条件。2022年2月，在一只母羊的左前肢双蹄上发现了远轴冠状带区域的溃疡性病变。活检组织学检查显示有角化过度和糜烂，伴有细胞外渗和结痂形成。密螺旋体属细菌PCR和荧光原位杂交（FISH）检测显示密螺旋体菌型1（PT1）呈阳性。此外，使用PCR可在活检组织中检测到结节类杆菌和牙龈卟啉单胞菌。局部单次应用金霉素喷雾剂后，两周内临床症状痊愈，在随后的两个月内未见复发。与患病绵羊饲养在一起的三只对照绵羊未表现出任何CODD的临床症状。通过PCR或FISH在趾间和冠状带活检组织中未发现密螺旋体属细菌。这是瑞士对CODD的首次描述，旨在提高兽医对CODD作为绵羊足部疾病鉴别诊断的认识。
