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在加拿大安大略省的省级行政数据中验证急诊科电复律程序。

Validating emergency department cardioversion procedures in provincial administrative data in Ontario, Canada.

机构信息

Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

ICES, Toronto, ON, Canada.

出版信息

PLoS One. 2022 Dec 1;17(12):e0277598. doi: 10.1371/journal.pone.0277598. eCollection 2022.

Abstract

BACKGROUND

Cardioversion of acute-onset atrial fibrillation (AF) via electrical or pharmacological means is a common procedure performed in many emergency departments. While these procedures appear to be very safe, the rarity of subsequent adverse outcomes such as stroke would require huge sample sizes to confirm that conclusion. Big data can supply such sample sizes.

OBJECTIVE

We aimed to validate several potential codes for successful emergency department cardioversion of AF patients.

METHODS

This study combined 3 observational datasets of emergency department AF visits seen at one of 26 hospitals in Ontario, Canada, between 2008 and 2012. We linked patients who were eligible for emergency department cardioversion to several province-wide health administrative datasets to search for the associated cardioversion billing and procedural codes. Using the observational data as the gold standard for successful cardioversion, we calculated the test characteristics of a billing code (Z437) and of procedural codes 1.HZ.09JAFS and 1.HZ.09JAJS. Both include pharmacological and electrical cardioversions, as well as unsuccessful attempts; the latter is <10% using electricity (in Canada, standard practice is to proceed to electrical cardioversion if pharmacological cardioversion is unsuccessful).

RESULTS

Of 4557 unique patients in the three datasets, 2055 (45.1%) were eligible for cardioversion. Nine hundred thirty-three (45.4%) of these were successfully cardioverted to normal sinus rhythm. The billing code had slightly better test characteristics overall than the procedural codes. Positive predictive value (PPV) of a billing was 89.8% (95% CI, 87.0-92.2), negative predictive value (NPV) 70.5% (95% CI, 68.1-72.8), sensitivity 52.1% (95% CI, 48.8-55.3), and specificity 95.1% (95% CI, 93.7-96.3).

CONCLUSIONS

AF patients who have been successfully cardioverted in an emergency department can be identified with high PPV and specificity using a billing code. Studies that require high sensitivity for cardioversion should consider other methods to identify cardioverted patients.

摘要

背景

通过电或药物手段对急性发作的心房颤动(AF)进行转复是许多急诊科常见的操作。虽然这些操作看起来非常安全,但后续出现诸如中风等不良结局的罕见性需要大量的样本量来证实这一结论。大数据可以提供这样的样本量。

目的

我们旨在验证几种用于急诊转复 AF 患者的潜在编码方法。

方法

本研究结合了加拿大安大略省 26 家医院 2008 年至 2012 年期间的 3 个急诊科 AF 就诊的观察性数据集。我们将符合急诊转复条件的患者与几个全省卫生管理数据集进行链接,以查找相关的转复计费和操作代码。使用观察性数据作为成功转复的金标准,我们计算了计费代码(Z437)和操作代码 1.HZ.09JAFS 和 1.HZ.09JAJS 的测试特征。这两个代码都包括药物和电转复,以及不成功的尝试;在加拿大,电转复如果不成功,标准做法是进行电转复(电转复的失败率<10%)。

结果

在三个数据集中,4557 个唯一患者中有 2055 个(45.1%)符合转复条件。其中 933 个(45.4%)患者成功转复为窦性心律。计费代码的整体测试特征略优于操作代码。计费代码的阳性预测值(PPV)为 89.8%(95%CI,87.0-92.2),阴性预测值(NPV)为 70.5%(95%CI,68.1-72.8),敏感性为 52.1%(95%CI,48.8-55.3),特异性为 95.1%(95%CI,93.7-96.3)。

结论

使用计费代码可以以高 PPV 和特异性识别急诊科成功转复的 AF 患者。对于需要高转复敏感性的研究,应考虑其他方法来识别转复患者。

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