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手枪放弃与自杀风险。

Handgun Divestment and Risk of Suicide.

机构信息

From the Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.

Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA.

出版信息

Epidemiology. 2023 Jan 1;34(1):99-106. doi: 10.1097/EDE.0000000000001549. Epub 2022 Sep 21.

Abstract

BACKGROUND

Firearm ownership is strongly related to suicide risk, yet little is known about how much risk declines when ownership ends ("divestment").

METHODS

Using data from 523,182 handgun owners, we estimated the effect of divesting and remaining divested versus never divesting on the risk of suicide and firearm-specific suicide. We used pooled logistic regression with inverse probability weighting, adjusting for demographic and area-level measures.

RESULTS

The 5-year risk of suicide death was 25.6 (95% confidence interval [CI] = 15.1, 37.2) per 10,000 persons with divestment and 15.2 (95% CI = 13.2, 17.3) per 10,000 persons with no divestment, corresponding to a risk difference of 10.4 (95% CI = 0.7, 21.1) per 10,000 persons. The 5-year risk of firearm-specific suicide death was 6.3 (95% CI = 1.4, 11.9) per 10,000 persons with divestment and 12.9 (95% CI = 11.0, 14.6) per 10,000 persons with no divestment, corresponding to a risk difference of -6.6 (95% CI = -11.4, -0.1) per 10,000 persons. Comparing divestment to no divestment, risks were elevated for deaths due to other causes proposed as negative control outcomes; we incorporated these estimates into a series of bias derivations to better understand the magnitude of unmeasured confounding.

CONCLUSIONS

Collectively, these estimates suggest that divestment reduces firearm suicide risk by 50% or more and likely reduces overall suicide risk as well, although future data collection is needed to fully understand the extent of biases such as unmeasured confounding.

摘要

背景

拥有枪支与自杀风险密切相关,但人们对拥有枪支者(“枪支持有者”)放弃枪支所有权后风险降低多少知之甚少。

方法

我们利用来自 523182 名手枪持有者的数据,估计了放弃和持续放弃与从不放弃枪支所有权对自杀风险和特定于枪支的自杀风险的影响。我们使用具有逆概率加权的汇总逻辑回归,调整了人口统计学和地区水平的措施。

结果

在 5 年内,枪支持有者的自杀死亡率为 25.6(95%置信区间[CI] = 15.1,37.2)/每 10000 人,与未放弃枪支者的 15.2(95% CI = 13.2,17.3)/每 10000 人相比,相应的风险差异为 10.4(95% CI = 0.7,21.1)/每 10000 人。在 5 年内,枪支持有者的特定于枪支的自杀死亡率为 6.3(95% CI = 1.4,11.9)/每 10000 人,与未放弃枪支者的 12.9(95% CI = 11.0,14.6)/每 10000 人相比,相应的风险差异为 -6.6(95% CI = -11.4,-0.1)/每 10000 人。与不放弃枪支相比,其他原因导致的死亡风险更高,这些原因被提出作为负对照结果;我们将这些估计值纳入一系列偏差推导中,以更好地了解未测量混杂的程度。

结论

这些估计结果表明,放弃枪支所有权可降低 50%或更多的枪支自杀风险,并且可能降低整体自杀风险,但需要进一步的数据收集来全面了解未测量混杂等偏倚的程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4acc/9719800/20aaf5ef01a3/ede-34-099-g001.jpg

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