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Successful Haploidentical Hematopoietic Stem Cell Transplantation with Azacitidine and Venetoclax Maintenance Therapy for Acute Myeloid Leukemia with Gene Fusion.

作者信息

Yuan Jiaojiao, Pei Renzhi, Lu Ying

机构信息

The Affiliated People’s Hospital of Ningbo University, Department of Hematology, Ningbo, Zhejiang, China

出版信息

Turk J Haematol. 2023 Feb 28;40(1):75-76. doi: 10.4274/tjh.galenos.2022.2022.0475. Epub 2022 Dec 2.

DOI:10.4274/tjh.galenos.2022.2022.0475
PMID:36458558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9979744/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/9979744/7057f0eaa887/TJH-40-75-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/9979744/7057f0eaa887/TJH-40-75-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4801/9979744/7057f0eaa887/TJH-40-75-g1.jpg

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Successful Haploidentical Hematopoietic Stem Cell Transplantation with Azacitidine and Venetoclax Maintenance Therapy for Acute Myeloid Leukemia with Gene Fusion.阿扎胞苷和维奈克拉维持治疗成功进行单倍体相合造血干细胞移植治疗基因融合的急性髓系白血病
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A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia.急性髓系白血病中一种类似急性早幼粒细胞白血病的新型 NUP98/RARG 基因融合。
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Allogeneic stem cell transplantation can prolong the survival of patients with NUP98-rearranged acute myeloid leukemia.异基因干细胞移植可延长NUP98重排的急性髓系白血病患者的生存期。
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Allogeneic hematopoietic stem cell transplantation for adult acute myeloid leukemia patients with nucleoporin 98 (NUP98) gene rearrangements: a real-world study in China.异基因造血干细胞移植治疗伴有核孔蛋白98（NUP98）基因重排的成人急性髓系白血病患者：一项中国的真实世界研究。
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引用本文的文献

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Front Oncol. 2025 Jul 30;15:1619296. doi: 10.3389/fonc.2025.1619296. eCollection 2025.
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Acute myeloid leukemia with NUP98::RARG rearrangement: a case report and review of the relevant literature.伴有NUP98::RARG重排的急性髓系白血病：一例报告及相关文献复习
Int J Hematol. 2025 Feb;121(2):265-271. doi: 10.1007/s12185-024-03881-2. Epub 2024 Dec 4.
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Case report: Successful therapy with azacitidine for acute myeloid leukemia with NUP98::RARG resembling acute promyelocytic leukemia.

本文引用的文献

1
Current views on the genetic landscape and management of variant acute promyelocytic leukemia.关于变异型急性早幼粒细胞白血病的遗传格局与管理的当前观点。
Biomark Res. 2021 May 6;9(1):33. doi: 10.1186/s40364-021-00284-x.
2
Acute Myeloid Leukemia with Gene Fusion Similar to Acute Promyelocytic Leukemia: Case Report and Literature Review.具有类似于急性早幼粒细胞白血病基因融合的急性髓系白血病：病例报告及文献综述
Onco Targets Ther. 2020 Oct 15;13:10559-10566. doi: 10.2147/OTT.S273172. eCollection 2020.
3
Alkaloid-based regimen is beneficial for acute myeloid leukemia resembling acute promyelocytic leukemia with NUP98/RARG fusion and RUNX1 mutation: A case report.
病例报告：阿扎胞苷成功治疗类似急性早幼粒细胞白血病的NUP98::RARG急性髓系白血病。
Front Oncol. 2024 Sep 4;14:1460557. doi: 10.3389/fonc.2024.1460557. eCollection 2024.
基于生物碱的方案对伴有NUP98/RARG融合和RUNX1突变的类似急性早幼粒细胞白血病的急性髓系白血病有益：一例报告。
Medicine (Baltimore). 2020 Oct 2;99(40):e22488. doi: 10.1097/MD.0000000000022488.
4
RARG Gene Dysregulation in Acute Myeloid Leukemia.急性髓系白血病中的视黄酸受体γ基因失调
Front Mol Biosci. 2019 Oct 24;6:114. doi: 10.3389/fmolb.2019.00114. eCollection 2019.
5
Update of the "Beijing Protocol" haplo-identical hematopoietic stem cell transplantation.《北京议定书》单倍体相合造血干细胞移植更新。
Bone Marrow Transplant. 2019 Aug;54(Suppl 2):703-707. doi: 10.1038/s41409-019-0605-2.
6
Clinical and molecular features of acute promyelocytic leukemia with variant retinoid acid receptor fusions.伴有变异维甲酸受体融合的急性早幼粒细胞白血病的临床和分子特征
Haematologica. 2019 May;104(5):e195-e199. doi: 10.3324/haematol.2018.205369. Epub 2018 Sep 20.
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Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States.单倍体相合造血干细胞移植：亚洲、欧盟和美国的全球比较概述
Biol Blood Marrow Transplant. 2016 Jan;22(1):23-6. doi: 10.1016/j.bbmt.2015.11.001. Epub 2015 Nov 10.
8
In vitro all-trans retinoic acid sensitivity of acute myeloid leukemia blasts with NUP98/RARG fusion gene.具有NUP98/RARG融合基因的急性髓系白血病原始细胞的体外全反式维甲酸敏感性
Ann Hematol. 2014 Nov;93(11):1931-3. doi: 10.1007/s00277-014-2073-5. Epub 2014 Apr 13.