Danielsen Elisabeth, Hansen Juliana Frohnert, Klose Marianne, Worm Dorte
Endokrinologisk Ambulatorium, Medicinsk Afdeling, Københavns Universitetshospital - Amager Hospital.
Afdeling for Hormon- og Stofskiftesygdomme, Københavns Universitetshospital - Rigshospitalet.
Ugeskr Laeger. 2022 Nov 28;184(48).
A 31-year-old woman was admitted to the local department of endocrinology for control of known anti-TPO positive hypothyroidism during pregnancy. The clinician noticed a remarkable hyperpigmentation. Primary adrenal insufficiency was diagnosed and treatment with cortico- and mineralosteroids commenced. Diagnosis of primary adrenal insufficiency during pregnancy is challenging as many symptoms overlap with normal symptoms of pregnancy. The usual diagnostic criteria cannot be used due to the altered hormone concentrations during pregnancy.
一名31岁女性因孕期已知的抗甲状腺过氧化物酶（anti-TPO）阳性甲状腺功能减退症的控制问题，入住当地内分泌科。临床医生注意到其有明显的色素沉着。诊断为原发性肾上腺皮质功能减退症，并开始使用皮质类固醇和盐皮质类固醇进行治疗。孕期原发性肾上腺皮质功能减退症的诊断具有挑战性，因为许多症状与正常孕期症状重叠。由于孕期激素浓度发生变化，通常的诊断标准无法使用。
