Department of General Surgery (Gastrointestinal Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Faculty Affairs and Human Resources Management Department, Southwest Medical University, Luzhou, China.
Scand J Gastroenterol. 2023 Jun;58(6):605-618. doi: 10.1080/00365521.2022.2152289. Epub 2022 Dec 2.
The aim of this systematic review and meta-analysis was to examine and assess the basic demographic characteristics and prevalence of comorbidities in acute mesenteric ischemia (AMI) and its various subtypes.
A literature search was conducted by using the databases PubMed, EMBASE, and Google Scholar (to June 1, 2022). Random-effects or fixed-effects models were selected to pool means and proportions and their corresponding 95% confidence intervals (CI), based on heterogeneity between studies. The results of meta-analyses for basic demographic characteristics and prevalence (proportions) of each specific comorbidities of acute mesenteric ischemia (AMI) and its various subtypes were described.
Ninety-nine studies were included in the meta-analysis, including 17,103 patients with AMI. Furthermore, 7941 patients with subclass diagnoses of AMI were identified, including 3,239 patients with arterial occlusive mesenteric ischemia (AOMI), 2,977 patients with nonocclusive mesenteric ischemia (NOMI), and 1,725 patients with mesenteric venous thrombosis (MVT). As a surgical emergency, AMI is associated with older patients and a high likelihood of multisystem comorbidities. Comorbidities of AMI involved multiple systemic diseases, including cardiovascular disease, endocrine and metabolic diseases, kidney diseases, digestive diseases, respiratory diseases, cerebrovascular diseases, vascular diseases, and cancer.
The basic demographic characteristics and the prevalence of comorbidities of different subtypes of AMI are different. The management of comorbidities should be an essential part of improving the prognosis of AMI patients and may contribute to precise prevention of AMI.
本系统评价和荟萃分析旨在检查和评估急性肠系膜缺血（AMI）及其各种亚型的基本人口统计学特征和合并症的患病率。
通过使用 PubMed、EMBASE 和 Google Scholar 数据库（截至 2022 年 6 月 1 日）进行文献检索。根据研究之间的异质性，选择随机效应或固定效应模型来汇总平均值和比例及其相应的 95%置信区间（CI）。描述了急性肠系膜缺血（AMI）及其各种亚型的基本人口统计学特征和每种特定合并症的患病率（比例）的荟萃分析结果。
共有 99 项研究纳入荟萃分析，包括 17103 例 AMI 患者。此外，还确定了 7941 例 AMI 亚类诊断患者，包括 3239 例动脉闭塞性肠系膜缺血（AOMI）、2977 例非闭塞性肠系膜缺血（NOMI）和 1725 例肠系膜静脉血栓形成（MVT）。作为一种外科急症，AMI 与老年患者和多系统合并症的可能性较高相关。AMI 的合并症涉及多种系统性疾病，包括心血管疾病、内分泌和代谢疾病、肾脏疾病、消化系统疾病、呼吸系统疾病、脑血管疾病、血管疾病和癌症。
不同亚型 AMI 的基本人口统计学特征和合并症的患病率不同。合并症的管理应成为改善 AMI 患者预后的重要组成部分，并可能有助于对 AMI 进行精确预防。
