舌下神经刺激治疗埃勒斯-当洛斯综合征患者的阻塞性睡眠呼吸暂停。
Treatment of obstructive sleep apnea with hypoglossal nerve stimulation in a patient with Ehlers-Danlos syndrome.
机构信息
Department of Otolaryngology, University of South Florida, Tampa, Florida.
Ear, Nose, and Throat Associates, Clearwater, Florida.
出版信息
J Clin Sleep Med. 2023 Mar 1;19(3):631-632. doi: 10.5664/jcsm.10368.
UNLABELLED
Ehlers-Danlos syndrome is a group of hereditary connective tissue disorders caused by defects in collagen synthesis and structure that manifests as tissue fragility, hypermobility, and vascular abnormalities. Patients with Ehlers-Danlos syndrome are at a high risk of developing obstructive sleep apnea due to increased tissue laxity in the upper airway, in addition to nasal-maxillary cartilaginous defects, scoliosis, or other abnormalities. Here we present the case of a patient with Ehlers-Danlos syndrome who underwent successful treatment of obstructive sleep apnea using hypoglossal nerve stimulation after continuous positive airway pressure therapy failure, demonstrating that this can be a useful treatment modality in this population.
CITATION
Miller SM, Miller MB. Treatment of obstructive sleep apnea with hypoglossal nerve stimulation in a patient with Ehlers-Danlos syndrome. . 2023;19(3):631-632.
背景
埃勒斯-当洛斯综合征是一组遗传性结缔组织疾病，由胶原合成和结构缺陷引起，表现为组织脆弱、过度活动和血管异常。由于上气道组织松弛增加，以及鼻上颌软骨缺陷、脊柱侧凸或其他异常，埃勒斯-当洛斯综合征患者发生阻塞性睡眠呼吸暂停的风险较高。这里我们报告了 1 例埃勒斯-当洛斯综合征患者，在持续气道正压通气治疗失败后，使用舌下神经刺激成功治疗了阻塞性睡眠呼吸暂停，表明这在该人群中是一种有用的治疗方法。
文献来源
Miller SM, Miller MB. Treatment of obstructive sleep apnea with hypoglossal nerve stimulation in a patient with Ehlers-Danlos syndrome.. 2023;19(3):631-632.
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