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vcfpop:基于下一代测序数据集对同源多倍体和非整倍体进行群体遗传学分析。

vcfpop: Performing population genetics analyses for autopolyploids and aneuploids based on next-generation sequencing data sets.

作者信息

Huang Kang, Li Wenkai, Yang Bing, Wang Dan, He Shujun, Shen Yujia, Ao Jincuo, Li Yuhang, Cui Yunxia, Kong Yuchen, Li Wei, Li Nianlong, Dunn Derek W, Li Baoguo

机构信息

Shaanxi Key Laboratory for Animal Conservation, College of Life Sciences, Northwest University, Xi'an, China.

Department of Forest and Conservation Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Mol Ecol Resour. 2025 Jul;25(5):e13744. doi: 10.1111/1755-0998.13744. Epub 2022 Dec 18.

Abstract

Polyploids are cells or organisms with a genome consisting of more than two sets of homologous chromosomes. Polyploid plants have important traits that facilitate speciation and are thus often model systems for evolutionary, molecular ecology and agricultural studies. However, due to their unusual mode of inheritance and double-reduction, diploid models of population genetic analysis cannot properly be applied to autopolyploids. To overcome this problem, we developed a software package entitled vcfpop to perform a variety of population genetic analyses for autopolyploids, such as parentage analysis, analysis of molecular variance, principal coordinates analysis, hierarchical clustering analysis and Bayesian clustering. We used three data sets to evaluate the capability of vcfpop to analyse large data sets on a desktop computer. This software is freely available at http://github.com/huangkang1987/vcfpop.

摘要

多倍体是指其基因组由两套以上同源染色体组成的细胞或生物体。多倍体植物具有促进物种形成的重要特征,因此常常是进化、分子生态学和农业研究的模式系统。然而,由于其特殊的遗传模式和双减数现象,群体遗传分析的二倍体模型无法适当地应用于同源多倍体。为克服这一问题,我们开发了一个名为vcfpop的软件包,用于对同源多倍体进行各种群体遗传分析,如亲权分析、分子方差分析、主坐标分析、层次聚类分析和贝叶斯聚类。我们使用三个数据集来评估vcfpop在台式计算机上分析大数据集的能力。该软件可在http://github.com/huangkang1987/vcfpop上免费获取。

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