从巴西南部屠宰犊牛中分离出的不同多重耐药性沙门氏菌血清型。

Different Multidrug-Resistant Salmonella spp. Serovars Isolated from Slaughter Calves in Southern Brazil.

机构信息

Centro de Pesquisa em Saúde Animal, Departamento de Diagnóstico e Pesquisa Agropecuária, Instituto de Pesquisas Veterinárias Desidério Finamor, Secretaria da Agricultura, Pecuária e Desenvolvimento Rural, Estrada Municipal do Conde, 6000, Sans Souci, Eldorado do Sul, RS, 92990-000, Brazil.

Faculdade de Agronomia e Medicina Veterinária, Programa de Pós-Graduação em Bioexperimentação, Universidade de Passo Fundo, BR 285, Campus I, São José, Passo Fundo, RS, 99052-900, Brazil.

出版信息

Curr Microbiol. 2022 Dec 2;80(1):11. doi: 10.1007/s00284-022-03136-5.

DOI:10.1007/s00284-022-03136-5

PMID:36459239

Abstract

Bovines are carriers of Salmonella spp., a relevant foodborne pathogen, acting as contamination sources in slaughterhouses. Calves are prone to infection, and antimicrobial resistance may occur in such bacteria. This study aimed to determine the prevalence and virulence determinants of Salmonella spp. recovered from calves in the Rio Grande do Sul state, Brazil. Eighty-five calves' carcasses were evaluated (leather and veal meat). Thirteen Salmonella spp. isolates (8%) from 11 animals (13%) were obtained only from leather, indicating that contamination occurred before slaughter and that the meat was safe regarding this aspect. The serotypes S. Minnesota, S. Abony, S. Cerro, and S. Gafsa were identified, and all isolates were multidrug-resistant. The isolates had at least 19 virulence-related genes, and the bla resistance gene was detected in three (23%). The data suggest that treating infections caused by these bacteria may be difficult in animals from these farms and can also be an extended human health problem.

摘要

牛是沙门氏菌的携带者，沙门氏菌是一种重要的食源性病原体，是屠宰场污染的来源。犊牛易感染，此类细菌可能存在抗生素耐药性。本研究旨在确定巴西南里奥格兰德州犊牛中分离出的沙门氏菌的流行情况和毒力决定因素。评估了 85 头犊牛的胴体（皮革和小牛肉）。仅从 11 头动物（13%）的 13 株沙门氏菌（8%）中获得了分离物，表明污染发生在屠宰前，并且从这方面来看，肉是安全的。鉴定出的血清型有 S. Minnesota、S. Abony、S. Cerro 和 S. Gafsa，所有分离株均为多药耐药株。分离株至少携带 19 种与毒力相关的基因，有 3 株（23%）检测到 bla 耐药基因。这些数据表明，来自这些农场的动物感染这些细菌可能难以治疗，也可能成为人类健康的一个长期问题。