Department of Obstetrics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Department of Obstetrics and Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Front Endocrinol (Lausanne). 2022 Nov 18;13:1029978. doi: 10.3389/fendo.2022.1029978. eCollection 2022.
To analyze pregnancy complications and outcomes of mothers with obesity or gestational diabetes mellitus (GDM).
15065 mothers were categorized into four and three groups by pre-pregnancy body mass index (preBMI) and abdominal circumference (AC), respectively, or divided into GDM or non-GDM groups. Logistic regression analysis was utilized to identify independent factors associated with pregnancy complications and outcomes.
The overweight and obesity groups accounted for 16.0% and 4.0% of the total population, respectively. GDM incidence rate was 12.3%. The overweight and obesity groups (pre-pregnancy body mass index [preBMI] ≥ 24 kg/m) were at higher risks for GDM, hypertensive disorders of pregnancy (HDP), gestational proteinuria, postpartum hemorrhage, preterm delivery, fetal malformation or stillbirth, neonatal asphyxia, large for gestational age (LGA), shoulder dystocia, and increased cesarean section rate. Similar results were obtained with AC grouping. GDM pregnant women had higher risks of HDP, preterm delivery, small for gestational age (SGA), LGA, and increased cesarean section rate.
People with obesity had a higher risk of adverse pregnancy outcomes. The recommended preBMI is 19.2-22.7 kg/m. The recommended AC at 11-13 gestational weeks is 74.0-84.0 cm, and that value in normal preBMI is 74.0-82.0 cm.
分析肥胖或妊娠期糖尿病（GDM）母亲的妊娠并发症及结局。
将 15065 名母亲按孕前体质量指数（preBMI）和腹围（AC）分为四组和三组，或分为 GDM 组和非 GDM 组。采用 logistic 回归分析确定与妊娠并发症及结局相关的独立因素。
超重和肥胖人群分别占总人群的 16.0%和 4.0%。GDM 发生率为 12.3%。超重和肥胖人群（preBMI≥24kg/m）发生 GDM、妊娠高血压疾病（HDP）、妊娠期蛋白尿、产后出血、早产、胎儿畸形或死胎、新生儿窒息、巨大儿（LGA）、肩难产和剖宫产率升高的风险更高。AC 分组也得到了类似的结果。GDM 孕妇发生 HDP、早产、小于胎龄儿（SGA）、LGA 和剖宫产率升高的风险更高。
肥胖人群发生不良妊娠结局的风险更高。推荐的 preBMI 为 19.2-22.7kg/m。推荐的 11-13 孕周 AC 值为 74.0-84.0cm，preBMI 正常时为 74.0-82.0cm。
