Chen Jia, Liu Jing, Liu Xin, Zeng Chudai, Chen Zhou, Li Shifu, Zhang Qian
Xiangya Nursing School, Central South University, Changsha, China.
The Chinese People's Liberation Army 921 Hospital of Joint Logistics Support Force, Department of General Practice, Changsha, China.
Front Vet Sci. 2022 Nov 18;9:1027453. doi: 10.3389/fvets.2022.1027453. eCollection 2022.
Studies on intracranial aneurysms (IAs) using animal models have evolved for decades. This study aimed to analyze major contributors and trends in IA-related animal research using bibliometric analysis.
IA-related animal studies were retrieved from the Web of Science database. Microsoft Excel 2010, GraphPad Prism 6, VOSviewer, and CiteSpace were used to collect and analyze the characteristics of this field.
A total of 273 publications were retrieved. All publications were published between 1976 and 2021, and the peak publication year is 2019. Rat model were used in most of the publications, followed by mice and rabbits. Japan (35.5%), the United States (30.0%), and China (20.1%) were the top three most prolific countries. Although China ranks third in the number of publications, it still lacks high-quality articles and influential institutions. was the most prolific journal that accepted publications related to IA research using animal models. has the highest impact factor with IA-related animal studies. Hashimoto N contributed the largest number of articles. Meng hui journal published the first and second highest cited publications. The keywords "subarachnoid hemorrhage," "macrophage," "rupture," "mice," "elastase," "gene," "protein," "proliferation," and "risk factors" might be a new trend for studying IA-related animal research.
Japan and the Unites States contributed the most to IA-related animal studies, in terms of both researchers and institutions. Although China ranks third in terms of the number of publications, it should strengthen the quality of its publications. Researchers should pay attention to the latest progress of , and for their high-quality IA-related animal studies. Using animal IA models, especially mice, to investigate the molecular mechanisms of IA may be the frontier topic now and in future.
使用动物模型对颅内动脉瘤（IA）的研究已经发展了几十年。本研究旨在通过文献计量分析来分析IA相关动物研究的主要贡献者和趋势。
从Web of Science数据库中检索IA相关的动物研究。使用Microsoft Excel 2010、GraphPad Prism 6、VOSviewer和CiteSpace来收集和分析该领域的特征。
共检索到273篇出版物。所有出版物发表于1976年至2021年之间，发表高峰年份为2019年。大多数出版物使用大鼠模型，其次是小鼠和兔子。日本（35.5%）、美国（30.0%）和中国（20.1%）是发表量最多的前三个国家。尽管中国在出版物数量上排名第三，但仍缺乏高质量文章和有影响力的机构。 是接受与使用动物模型的IA研究相关出版物最多的期刊。 在IA相关动物研究方面具有最高的影响因子。桥本N贡献的文章数量最多。《孟辉杂志》发表了被引次数最高的前两篇出版物。关键词“蛛网膜下腔出血”“巨噬细胞”“破裂”“小鼠”“弹性蛋白酶”“基因”“蛋白质”“增殖”和“危险因素”可能是IA相关动物研究的新趋势。
在研究人员和机构方面，日本和美国对IA相关动物研究的贡献最大。尽管中国在出版物数量上排名第三，但应加强出版物质量。研究人员应关注 以及 的高质量IA相关动物研究的最新进展。使用动物IA模型，尤其是小鼠，来研究IA的分子机制可能是现在和未来的前沿课题。
