Khorzhevskii V A, Ermachenko D A, Gappoev S V, Levkovich L G
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia.
Krasnoyarsk State Regional Bureau of Pathology, Krasnoyarsk, Russia.
Arkh Patol. 2022;84(6):52-55. doi: 10.17116/patol20228406152.
The article presents a rare case of bone marrow metastasis of the spleen angiosarcoma. The observation is of particular interest due to the fact that secondary bone marrow damage in angiosarcoma in the vast majority of cases is due by primary tumor growth in the spleen. Clinically, such cases may resemble the course of blood diseases with hematological disorders and splenomegaly. Patients come into the field of view of a hematologist, and the final diagnosis is unexpected to the attending physician. Detection of angiosarcoma growth in a bone marrow trephine biopsy during morphological examination can be a rare finding for a pathologist. In this regard, the presented case is of interest not only for pathologists, but also for doctors of clinical specialties.
本文介绍了一例罕见的脾脏血管肉瘤骨髓转移病例。由于在绝大多数情况下，血管肉瘤的继发性骨髓损害是由脾脏原发性肿瘤生长所致，因此该病例特别值得关注。临床上，此类病例可能类似于伴有血液系统疾病和脾肿大的血液疾病病程。患者进入血液科医生的视野，而最终诊断对于主治医生来说是出乎意料的。在形态学检查中，骨髓穿刺活检发现血管肉瘤生长对病理学家来说可能是罕见的发现。在这方面，本文介绍的病例不仅对病理学家，而且对临床专科医生都具有重要意义。
