Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
J Allergy Clin Immunol Pract. 2023 Feb;11(2):602-609.e1. doi: 10.1016/j.jaip.2022.11.022. Epub 2022 Dec 5.
Rhinitis medicamentosa (RM) is a type of nonallergic rhinitis caused by prolonged use of nasal decongestants (NDs). Although it is a preventable phenotype of rhinitis, little is known about patients dealing with this condition.
To gain a better understanding of patients' views and experiences of ND overuse, and potential facilitators and barriers to discontinue the overuse.
We performed a qualitative study using in-depth semistructured interviews with 22 patients who have been using an ND on an almost daily basis for at least 6 months. The interviews were conducted face-to-face, audio-recorded, and transcribed verbatim. Data analysis followed the grounded theory approach.
Interviewees described the large impact of nasal congestion on their daily lives. Despite efforts to try other treatment options, the ND was considered the only effective aid to resolve the troublesome symptom. Most participants were aware that the prolonged use was problematic, sometimes leading to hiding behavior in order to avoid criticism by others including their health professionals. Many participants expressed a strong will to discontinue. However, multiple barriers to withdrawal were identified including fear of surgery or the impact of withdrawal on sleep, lack of good alternatives, and negative experiences with past withdrawal attempts. Patients thus face a dilemma in which the barriers to withdrawal currently outweigh the possible benefits.
The use of NDs is considered indispensable by many chronic users. The facilitators and barriers identified in this study provide opportunities to reduce the use of NDs and the prevalence of RM in the future.
药物性鼻炎(RM)是一种由长期使用鼻减充血剂(NDs)引起的非过敏性鼻炎。虽然它是一种可预防的鼻炎表型,但对于患有这种疾病的患者的了解甚少。
更好地了解患者对 ND 过度使用的看法和体验,以及停止过度使用的潜在促进因素和障碍。
我们采用定性研究方法,对 22 名患者进行了深入的半结构化访谈,这些患者每天至少使用 ND 长达 6 个月。访谈是面对面进行的,录音并逐字转录。数据分析遵循扎根理论方法。
受访者描述了鼻塞对他们日常生活的巨大影响。尽管他们努力尝试其他治疗方案,但 ND 被认为是唯一有效缓解这一恼人症状的方法。大多数参与者都意识到长期使用存在问题,有时为了避免他人(包括他们的医疗保健专业人员)的批评而采取隐藏行为。许多参与者表示强烈希望停止使用。然而,确定了多种停药障碍,包括对手术的恐惧或停药对睡眠的影响、缺乏良好的替代品以及过去停药尝试的负面经历。因此,患者面临着一个困境,即目前停药的障碍超过了可能的益处。
许多慢性使用者认为 NDs 的使用是不可或缺的。本研究中确定的促进因素和障碍为减少未来 ND 的使用和 RM 的流行提供了机会。