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药剂师对长期使用鼻减充血剂的态度:一项横断面研究。

Pharmacists' Attitudes Towards Long-Term Use of Nasal Decongestants: A Cross-Sectional Study.

作者信息

Mokhatrish Mohammad M, Almatrafi Sharif D, Aldrees Turki M, Aldriweesh Turki A, AlGhamdi Fahad M, Al-Dosary Abdullah S, Alhumaydani Naif K, Aldakkan Osamah Z, Alrudian Naif, Ali Ali Hassan

机构信息

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia.

Department of Family Medicine & Polyclinics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

出版信息

J Multidiscip Healthc. 2024 Mar 13;17:1079-1090. doi: 10.2147/JMDH.S451835. eCollection 2024.

Abstract

BACKGROUND

Rhinitis medicamentosa is a nonallergic inflammation of the nasal mucosa caused by topical decongestants overuse. It mainly affects young and middle-aged adults. Therefore, the aim of this study was to investigate the attitudes of pharmacists regarding the utilization of over-the-counter intranasal decongestants.

METHODS

An online cross-sectional study was conducted from November 2021 to January 2022. The target population of the study included pharmacists who work in community pharmacies in Saudi Arabia. Binary logistic regression analysis was used to identify predictors of having positive attitude towards controlling the use of decongestant.

RESULTS

A total of 220 participants were included in this study. Around 15.0% of them reported that ND come with a physician prescription. The majority of the participants (87.3%) reported that the less than 5 days is the maximum safe duration for the use of NDs. Overall, the study participants demonstrated moderately positive attitude towards controlling the use of decongestant with a mean attitude score of 2.5 (standard deviation: 1.2) out of 5; which represents 50.0% of the maximum score. Binary logistic regression analysis identified that pharmacists aged 31-40 years were two-folds more likely to have positive attitude towards controlling the use of decongestant compared to others (p<0.05). Around 45.9% of them reported that they recommend other over-the-counter treatments like nasal irrigation, nasal steroids, or antihistamine if they see a patient with RM asking for ND with or without prescription.

CONCLUSION

The majority of pharmacists in Saudi Arabia demonstrated sufficient awareness and understanding on the adverse effects associated with the excessive use of NDs. Rhinitis medicamentosa can be avoided by appropriate measures, highlighting the importance of raising awareness about the excessive use of decongestants among healthcare professionals and patients alike.

摘要

背景

药物性鼻炎是一种因局部减充血剂过度使用引起的鼻黏膜非过敏性炎症。它主要影响中青年成年人。因此,本研究的目的是调查药剂师对非处方鼻用减充血剂使用的态度。

方法

于2021年11月至2022年1月进行了一项在线横断面研究。该研究的目标人群包括在沙特阿拉伯社区药房工作的药剂师。采用二元逻辑回归分析来确定对控制减充血剂使用持积极态度的预测因素。

结果

本研究共纳入220名参与者。其中约15.0%报告说鼻用减充血剂需要医生处方。大多数参与者(87.3%)报告说,使用鼻用减充血剂的最长安全时长为不到5天。总体而言,研究参与者对控制减充血剂的使用表现出中度积极的态度,平均态度得分为2.5(标准差:1.2)(满分5分);这代表了最高分的50.0%。二元逻辑回归分析表明,31 - 40岁的药剂师对控制减充血剂使用持积极态度的可能性是其他人的两倍(p<0.05)。其中约45.9%报告说,如果他们看到患有药物性鼻炎的患者无论有无处方都索要鼻用减充血剂,他们会推荐其他非处方治疗方法,如鼻腔冲洗、鼻用类固醇或抗组胺药。

结论

沙特阿拉伯的大多数药剂师对过度使用鼻用减充血剂的不良反应表现出了足够的认识和理解。通过适当措施可以避免药物性鼻炎,这凸显了提高医护人员和患者对过度使用减充血剂认识的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8808/10949306/50a0adb66de2/JMDH-17-1079-g0001.jpg

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