台湾青年脑卒中的长期死亡率：一项基于人群的十年流行病学研究。
Long-term mortality rates of young stroke in Taiwan: A decade-long epidemiology population-based study.
作者信息
Wu Yu-Ying, Chen Po-Yuan, Wu Cheng-Chun, Chen Han-Jung, Liang Cheng-Loong, Lee Yi-Che, Lin Chi-Wei, Hung Chao-Ming, Lin I-Fan, Wang Hao-Kuang
机构信息
School of Medicine, College of Medicine, I-Shou University, Kaohsiung.
Department of Neurosurgery, E-Da Hospital, Kaohsiung.
出版信息
Eur Stroke J. 2022 Dec;7(4):447-455. doi: 10.1177/23969873221115268. Epub 2022 Jul 22.
INTRODUCTION
Stroke remains a leading cause of death worldwide. Stroke in young adults is an important issue, gaining extra attention in recent years. This study aims to investigate the mortality after stroke in young adults in Taiwan.
PATIENTS AND METHODS
This is a registry- and population-based study in Taiwan of patients aged 20-50 years with first-ever stroke between 1999 and 2012, with follow-up until January 1, 2022. Patients and mortalities were identified through Taiwan National Health Insurance database.
RESULTS
The study population included 65,097 patients with stroke (mean age, 42.6 ± 6.6 years; 30.5% woman). There were 23,481 (36.1%) intracranial hemorrhage, 37,522 (57.6%) ischemic stroke, and 4094 (6.3%) stroke not otherwise specified. At the end of follow-up, a total of 18,248 deaths (28.0%) occurred during a median follow-up of 9.8 years (interquartile range, 6.4-13.7 years).
CONCLUSION
Taiwan young adults who were 30-day survivors of first-ever stroke have significantly higher long-term mortality rates when compared to other population-based studies.
引言
中风仍然是全球主要的死亡原因。年轻人中风是一个重要问题，近年来受到了更多关注。本研究旨在调查台湾年轻人中风后的死亡率。
患者与方法
这是一项基于台湾登记处和人群的研究，研究对象为1999年至2012年间首次中风的20至50岁患者，随访至2022年1月1日。通过台湾国民健康保险数据库识别患者和死亡情况。
结果
研究人群包括65097例中风患者（平均年龄42.6±6.6岁；女性占30.5%）。其中有23481例（36.1%）颅内出血，37522例（57.6%）缺血性中风，4094例（6.3%）未另行指定的中风。随访结束时，在中位随访9.8年（四分位间距为6.4 - 13.7年）期间，共发生18248例死亡（28.0%）。
结论
与其他基于人群的研究相比，台湾首次中风后存活30天的年轻人长期死亡率显著更高。
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