Ha Ju-Young, Park Hyo-Jin, Ban Seon-Hwa
College of Nursing, Pusan National University, Yangsan, Korea.
Korea Disease Control and Prevention Agency, Cheongju, Korea.
J Psychosom Obstet Gynaecol. 2023 Dec;44(1):2142777. doi: 10.1080/0167482X.2022.2142777.
This study aimed to analyze the efficacy of psychosocial interventions for improving pregnancy rates in infertile women undergoing fertilization (IVF) treatment through a systematic review and meta-analysis.
Twelve studies were included in the meta-analysis. To estimate the effect size, a meta-analysis of the studies was performed using RevMan 5.3. The possibility of publication bias was evaluated using funnel plots and Egger's method.
A statistically significant effect size (standardized mean difference [SMD] = 1.39; 95% confidence interval [CI] = 1.11-1.71; = 0.004; = 19%) was found for the 12 studies that investigated the effects of psychosocial interventions on clinical pregnancy rates. The psychosocial interventions that had a significant effect on pregnancy rates were mind-body interventions (SMD = 1.37; 95% CI = 1.01-1.85; = 0.040; = 0%) and cognitive behavioral therapy (SMD = 2.19; 95% CI = 1.17-4.13; = 0.010).
The results suggest that psychosocial interventions affect pregnancy rates. Moreover, they indicate that mind-body interventions and cognitive behavioral therapy are beneficial for improving the pregnancy outcome in infertile women undergoing IVF.
本研究旨在通过系统评价和荟萃分析，分析心理社会干预对接受体外受精（IVF）治疗的不孕女性提高妊娠率的疗效。
12项研究纳入荟萃分析。为估计效应量，使用RevMan 5.3对这些研究进行荟萃分析。采用漏斗图和埃格法评估发表偏倚的可能性。
在12项调查心理社会干预对临床妊娠率影响的研究中，发现效应量具有统计学意义（标准化均数差[SMD]=1.39；95%置信区间[CI]=1.11-1.71；P=0.004；I²=19%）。对妊娠率有显著影响的心理社会干预措施是身心干预（SMD=1.37；95%CI=1.01-1.85；P=0.040；I²=0%）和认知行为疗法（SMD=2.19；95%CI=1.17-4.13；P=0.010）。
结果表明心理社会干预会影响妊娠率。此外，还表明身心干预和认知行为疗法有利于改善接受IVF治疗的不孕女性的妊娠结局。
