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肝移植受者的脑暗色丝孢霉病:一例报告。

Cerebral phaeohyphomycosis in liver transplant recipient: A case report.

作者信息

Ullah Kaleem, Baig Muhammad Asif, Dogar Abdul Wahab, Uddin Shams, Fatir Chaudhary Abdul, Asad Ali, Tahir Muhammad Junaid, Lee Ka Yiu, Mohamed Ahmed Khabab Abbasher Hussien, Yousaf Zohaib

机构信息

Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences Gambat Pakistan.

Lahore General Hospital Lahore Pakistan.

出版信息

Clin Case Rep. 2022 Dec 5;10(12):e6691. doi: 10.1002/ccr3.6691. eCollection 2022 Dec.

Abstract

Cerebral phaeohyphomycosis is a fungal brain infection with a high fatality rate. It is caused by dematiaceous fungi and is increasingly recognized as a cause of serious illness in both immunocompetent and immunocompromised patients. We report cerebral phaeohyphomycosis in a liver transplant recipient. He was treated with multiple surgeries and antifungals and made a complete recovery. This report highlights that early and aggressive surgical intervention and extended antifungal coverage can have a positive outcome even in immunocompromised patients. The fungal infection in immunocompromised patients should be considered and treated aggressively.

摘要

脑暗色丝孢霉病是一种病死率很高的真菌性脑部感染。它由暗色真菌引起,越来越被认为是免疫功能正常和免疫功能低下患者严重疾病的病因。我们报告了一例肝移植受者发生的脑暗色丝孢霉病。他接受了多次手术和抗真菌治疗,并完全康复。本报告强调,即使在免疫功能低下的患者中,早期积极的手术干预和延长抗真菌治疗范围也可产生积极结果。应考虑免疫功能低下患者的真菌感染并积极进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5fa/9723403/61d925fef3bf/CCR3-10-e6691-g001.jpg

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