Lee Y N
West J Med. 1978 Nov;129(5):374-80.
The rationale and results of clinical use of carcinoembryonic antigen (CEA) tests in patients with carcinoma of the breast and colon deserve review. Plasma CEA levels have been found to correlate with the extent of tumor invasion and site of metastatic spread, and CEA titers have diagnostic and prognostic value. Although postresectional serial CEA testing is not as useful in cases of breast carcinoma, in cases of carcinoma of the colon it may indicate recurrence or progression of the lesion. However, there are limitations and CEA results should be interpreted in conjunction with other clinical information.
乳腺癌和结肠癌患者癌胚抗原(CEA)检测的临床应用原理及结果值得探讨。血浆CEA水平已被发现与肿瘤侵袭范围和转移扩散部位相关,CEA滴度具有诊断和预后价值。虽然术后连续CEA检测在乳腺癌病例中用处不大,但在结肠癌病例中它可能提示病变复发或进展。然而,CEA检测存在局限性,其结果应结合其他临床信息进行解读。