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围产期静脉-静脉体外膜肺氧合治疗严重 COVID-19 相关急性呼吸窘迫综合征患者。

Peripartum veno-venous extracorporeal membrane oxygenation in patients with severe CoViD-19-related-ARDS.

机构信息

Cardiac Critical Care and ECMO, Critical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Critical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

出版信息

Perfusion. 2024 Mar;39(2):426-432. doi: 10.1177/02676591221144729. Epub 2022 Dec 9.

Abstract

We describe a case series of five pregnant or postpartum women with severe CoViD-19-related ARDS requiring VV ECMO at our centre between Jan 1 and Sep 30, 2021. All patients were cannulated at the referring hospitals by our team before transferring to our centre. None of the women were vaccinated against CoViD-19. All had severe ARDS with Murray's Lung Injury Score of 3-4 and met the severity threshold for ECMO initiation that was used in the EOLIA study. All patients were discharged alive to home, acute rehabilitation, or lung transplant centre. One patient suffered intrauterine death before ECMO initiation and another while on ECMO. VV ECMO for refractory CoViD-19 related ARDS in the peripartum period is safe, and in this small series, it was associated with good maternal survival rates.

摘要

我们描述了 5 例在我们中心于 2021 年 1 月 1 日至 9 月 30 日期间因严重 CoViD-19 相关 ARDS 需要 VV ECMO 的妊娠或产后妇女的病例系列。所有患者均由我们的团队在转至我们中心之前在转诊医院进行置管。这些妇女均未接种过 CoViD-19 疫苗。所有患者均患有严重的 ARDS,Murray 肺损伤评分 3-4 分,并符合 EOLIA 研究中用于 ECMO 启动的严重程度阈值。所有患者均存活出院至家庭、急性康复或肺移植中心。一名患者在 ECMO 启动前发生宫内死亡,另一名患者在 ECMO 期间发生死亡。VV ECMO 治疗围产期难治性 CoViD-19 相关 ARDS 是安全的,在这个小系列中,它与良好的产妇生存率相关。

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Extra-Corporeal Membrane Oxygenation in Pregnancy.孕期体外膜肺氧合
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