腹部近红外光谱技术可用于可靠测量早产儿内脏氧合变化。
Abdominal Near Infrared Spectroscopy can be reliably used to measure splanchnic oxygenation changes in preterm infants.
机构信息
Neonatal unit, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.
Neonatal unit, Homerton Healthcare NHS Foundation Trust, London, UK.
出版信息
J Perinatol. 2023 Jun;43(6):716-721. doi: 10.1038/s41372-022-01576-2. Epub 2022 Dec 10.
OBJECTIVE
Near-infrared spectroscopy (NIRS) allows assessment of regional tissue oxygen delivery and extraction. There are doubts regarding reliability of gut NIRS measurements. This study assesses reliability of NIRS for monitoring gut oxygenation.
STUDY DESIGN
Splanchnic tissue haemoglobin index (sTHI), tissue oxygenation index (sTOI) and fractional tissue oxygen extraction (sFTOE) changes during blood transfusion were measured using NIRS and compared to stable control infants. Infants were grouped into 3 chronological age groups: 1-7, 8-28 and ≥29 days of life.
RESULTS
sTHI, sTOI significantly increased, and sFTOE reduced following blood transfusion in all age group infants (n = 59), with no changes seen in control infants (n = 12). Baseline characteristics including gestational age and feed volumes did not differ between groups.
CONCLUSION
Gut perfusion measured by NIRS improved in infants who received blood transfusion, a change not seen in the control group, thus suggesting NIRS is a reliable method to measure splanchnic tissue oxygenation.
目的
近红外光谱（NIRS）可用于评估局部组织的氧输送和摄取。肠道 NIRS 测量的可靠性存在疑问。本研究评估了 NIRS 监测肠道氧合的可靠性。
研究设计
使用 NIRS 测量输血期间内脏组织血红蛋白指数（sTHI）、组织氧指数（sTOI）和组织氧摄取分数（sFTOE）的变化，并与稳定的对照婴儿进行比较。婴儿分为 3 个年龄组：1-7 天、8-28 天和≥29 天。
结果
所有年龄组婴儿（n=59）输血后 sTHI、sTOI 显著增加，sFTOE 降低，而对照组婴儿（n=12）无变化。基线特征包括胎龄和喂养量在组间无差异。
结论
接受输血的婴儿肠道灌注通过 NIRS 得到改善，而对照组未见变化，这表明 NIRS 是测量内脏组织氧合的可靠方法。
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