Chang Sing-Ya, Lee Chih-Chun, Chang Ming-Ling, Teng Wen-Chieh, Hsiao Chao-Yang, Yu Han-Hua, Hsieh Meng-Ju, Chan Tien-Ming
School of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Department of Medical Education, Chang Gung Memorial Hospital, Keelung Branch, Keelung 204, Taiwan.
J Clin Med. 2022 Nov 22;11(23):6887. doi: 10.3390/jcm11236887.
Kimura disease (KD) is a rare, chronic proliferative condition presenting as a subcutaneous mass predominantly located in the head and neck region; it is characterized by eosinophilia and elevated serum IgE levels. IgG4-related disease (IgG4RD) is a fibroinflammatory condition characterized by swelling in single or multiple organs and the infiltration of IgG4 plasma cells. Herein, we presented two cases. Case 1 is a 38-year-old man with a painless mass in his right postauricular region, and Case 2 is a 36-year-old man with painless lymphadenopathy in his bilateral postauricular region. After surgical excision, they showed good recovery with no relapse. Although Cases 1 and 2 shared several overlapping pathological manifestations, there were a few differences that allowed the differentiation of KD and IgG4RD.
木村病（KD）是一种罕见的慢性增殖性疾病，表现为主要位于头颈部区域的皮下肿块；其特征为嗜酸性粒细胞增多和血清IgE水平升高。IgG4相关性疾病（IgG4RD）是一种纤维炎性疾病，其特征为单个或多个器官肿胀以及IgG4浆细胞浸润。在此，我们报告了两例病例。病例1是一名38岁男性，右耳后区域有一无痛性肿块；病例2是一名36岁男性，双侧耳后区域有无痛性淋巴结病。手术切除后，他们恢复良好，无复发。尽管病例1和病例2有一些重叠的病理表现，但仍存在一些差异，有助于区分木村病和IgG4相关性疾病。
