Reddy Suraj Jayadeva, Reddy Bathi Sourabh, Chawla Arun, de la Rosette Jean J M C H, Laguna Pilar, Hegde Padmaraj, Shah Abhijit, Choudhary Anupam, Kankaria Sanket, Hiremath Vivekanand Kedarlingayya
Department of Urology and Renal Transplantation, Kasturba Medical College, MAHE, Manipal 576104, Karnataka, India.
Istanbul Medipol Mega University Hospital, Istanbul 34214, Turkey.
J Clin Med. 2022 Nov 28;11(23):7023. doi: 10.3390/jcm11237023.
Ureteric stent insertion following ureteroscopic lithotripsy (URSL) is a common and widely accepted procedure. However, there is no agreement on whether a ureteric stent should be placed following an uncomplicated URSL. Furthermore, the definition of uncomplicated URSL remains debatable. To compare the efficacy, safety, and morbidity of no stent placement with the conventional stent placement after uncomplicated retrograde semirigid URS for a distal ureteric calculus of size ≤1 cm, we compared the corresponding complication rates, emergency visits, secondary interventions, and pain at follow-up. Following an uncomplicated ureteroscopic lithotripsy, 104 patients were randomized into the conventional stented group (CSG) and nonstented group (NSG). Lower urinary tract symptoms and sexual function were evaluated using validated questionnaires (IPSS + IIEF-5 + MSHQ-EjD/FSFI) preoperatively and at 4 weeks during follow-up. Pain scores at follow-up were recorded using a visual analogue scale (VAS). Patients who visited the emergency room or needed secondary interventions before the recommended follow-up time were noted. The Generalized Estimating Equations method was used to explore the difference in change in the domains of IPSS, IIEF-5, MSHQ-EjD, and FSFI between the two groups over time. A significant difference was noted in the following IPSS domains: Frequency, Urgency, Nocturia, Storage Symptoms, Total IPSS Score ( ≤ 0.001), and QoL ( = 0.002); IIEF-5 domains: Overall Score ( = 0.004); MSHQ-EjD domains: Ejaculation Bother/Satisfaction ( ≤ 0.001); and FSFI domains: Lubrication ( ≤ 0.001), Satisfaction ( = 0.006), and Overall Score ( = 0.004). There was no significant difference between the various groups in terms of distribution of emergency visits, readmission and secondary interventions, pain at follow-up (VAS), and need for long-term analgesia. Nonplacement of stents after uncomplicated URS decreases stent-related symptoms and preserves QoL without placing the patient under increased postoperative risk.
输尿管镜碎石术(URSL)后插入输尿管支架是一种常见且被广泛接受的操作。然而,对于无并发症的URSL后是否应放置输尿管支架尚无定论。此外,无并发症的URSL的定义仍存在争议。为了比较无支架置入与传统支架置入在治疗直径≤1 cm的远端输尿管结石的无并发症逆行半硬性URSL后的疗效、安全性和发病率,我们比较了相应的并发症发生率、急诊就诊情况、二次干预措施以及随访时的疼痛情况。在无并发症的输尿管镜碎石术后,104例患者被随机分为传统支架置入组(CSG)和无支架组(NSG)。术前及随访4周时使用经过验证的问卷(IPSS + IIEF-5 + MSHQ-EjD/FSFI)评估下尿路症状和性功能。随访时使用视觉模拟量表(VAS)记录疼痛评分。记录在推荐的随访时间之前到急诊室就诊或需要二次干预措施的患者。采用广义估计方程法探讨两组在随访期间IPSS、IIEF-5、MSHQ-EjD和FSFI各领域变化的差异。在以下IPSS领域观察到显著差异:尿频、尿急、夜尿、储尿期症状、总IPSS评分(≤0.001)和生活质量(=0.002);IIEF-5领域:总分(=0.004);MSHQ-EjD领域:射精困扰/满意度(≤0.001);以及FSFI领域:润滑(≤0.001)、满意度(=0.006)和总分(=0.004)。在急诊就诊、再次入院和二次干预措施的分布、随访时的疼痛(VAS)以及长期镇痛需求方面,各组之间无显著差异。无并发症的URSL后不放置支架可减少与支架相关的症状并保留生活质量,且不会增加患者的术后风险。